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A class of anti-inflammatory drugs already FDA-approved for rheumatoid arthritis could “purge” the reservoir of infected immune cells in people infected by HIV, according to new research. When culturing cells from HIV-infected individuals, researchers found the medications tofacitinib and…

Fish sense water motion the same way humans sense sound, according to new research out of Case Western Reserve University School of Medicine. Researchers discovered a gene also found in humans helps zebrafish convert water motion into electrical impulses that are sent to the brain for perception.…

Four-fold improvement in hearing for a mouse model of deafness A research advance co-led by Case Western Reserve University School of Medicine’s Kumar Alagramam may stop the progression of hearing loss and lead to significant preservation of hearing in people with Usher syndrome type III, a form…

In a pair of publications, researchers have shown how cells adapt to stressors—like water loss—by reprogramming their internal signaling networks. The studies describe previously unknown mechanisms that cells use to send signals between cellular machinery and avoid cell death. According to the…

Squamous cell carcinoma of the tongue, also known as oral tongue cancer, is an aggressive form of cancer that generally affects older people. Patients with the disease often find it difficult to eat, swallow food, or speak. Reasons for its generally poor prognosis include late detection, before…

Will probe link among cell-signaling defects, rapid cell growth and enlarged brains One hypothesis for how autism develops is excessive neuron production in the prenatal period, leading to a transient but significant increase in brain size in the first few years of life in about one-quarter of…

Case Comprehensive Cancer Center at Case Western Reserve University School of Medicine has been awarded a $100,000 Josh Metzger Memorial Fox Trot Grant sponsored by the Prayers From Maria Foundation, in support of pediatric neurosurgical oncology research. Violette Recinos, MD, director of…

The most lethal form of breast cancer could have a new treatment option, according to new research out of the Case Comprehensive Cancer Center at Case Western Reserve University School of Medicine. In the Proceedings of the National Academy of Sciences, researchers showed triple-negative breast…

Case Western Reserve researcher tests new methods to anchor wind turbines, part of LEEDCo, Icebreaker Windpower project There are lots of moving parts to bringing the world’s first freshwater wind turbines to Lake Erie by 2018, but Case Western Reserve University researchers are focused on keeping…

One hypothesis for how autism develops is excessive neuron production in the prenatal period, leading to a transient but significant increase in brain size in the first few years of life in about one-quarter of children with the disease. But the precise timing and cause of this overgrowth is poorly…