EMMANUEL CHURCH (EPISCOPAL) dated from 1871, when ST. PAUL'S EPISCOPAL at Euclid and Case (E. 40th) St. opened Emmanuel Chapel at Prospect and Hayward (E. 36th) streets. Still under the supervision of St. Paul's, a new Emmanuel Chapel was built in 1874 on EUCLID AVE. east of Glen Park Place (E. 86th St.); in 1876 it was admitted to the Episcopal Diocese of Ohio as Emmanuel Church. In 1880 the frame Gothic building was moved slightly west and enlarged. In 1889 conflict resulted in the rector and a large number of parishioners leaving the Episcopal church altogether. They formed the Church of the Epiphany, Reformed Episcopal, and built a church on the other side of Euclid Ave. A period of growth for Emmanuel followed: a Sunday school was started in 1890 and a chapel in 1892, which later became St. Alban's Parish.
In 1900 the firm of Cram, Goodhue, & Ferguson designed a new building for the Euclid Ave. site (8604 Euclid). A late Gothic Revival structure of stone, it was built as funds became available. The first section, 6 bays of the nave and a temporary chancel, was built in 1902. The remaining 2 bays and the interior were completed in 1904. A new brick and stone parish house replaced the older wooden one in 1924, but the tower of the original plan remained uncompleted. With the sale of adjoining property, the building debt was liquidated and the church consecrated in 1926. The parish was in the center of great social and economic change in the neighborhood during the 1950s-1970s. To remain viable, a variety of programs were started, including tutoring, legal aid, and a hunger center serving as many as 1,900 families per month.
In Oct. of 1991, Emmanuel Church merged with Incarnation Church, an Episcopal congregation originally established in 1891 at E. 105th and St. Clair, which later moved to a building at Ramona Blvd. The combined congregation remained in Emmanuel's Euclid Ave. building, which was renamed the Church of the Transfiguration. Incarnation's building was sold to Damascus Baptist Church after the merger.
In 2010, the church was razed by a fire, leaving only the stone walls intact. It was deemed to be a public safety hazard if not repaired or demolished. With quotes for repairs between six to eight million dollars, it was deemed to be simply too expensive to restore. In 2012, the Cleveland Clinic bought the vacant property, and a demolition permit was approved in 2013. The church was torn down in 2014. As of 2021, a Clinic-owned Holiday Inn now stands on the lot.