Timothy J. Mead, PhD

Assistant Professor
Department of Pediatrics
School of Medicine
Staff Scientist
Department of Pediatrics
University Hospitals Cleveland Medical Center

Research Information

Research Interests

Dr. Mead is a trained developmental and molecular biologist with a keen focus on cardiovascular development and disease. His research centers on how changes in the extracellular matrix results in dysfunctional heart development and resulting congenital heart defects. Dr. Mead utilizes mouse models of congenital heart disease, biochemistry and proteomics to understand the molecular mechanisms underlying these diseases towards the development of therapeutic approaches. His current research focus is on the novel concept of inhibiting a protease that remodels fibrillin microfibrils in the aorta in an effort to identify a therapeutic for Marfan syndrome.