- Sleep apnea and other sleep related disorders
- Disorders of minimal brain dysfunction (i.e. attention deficit hyperactivity disorder [ADHD])
Our laboratory focuses on the identification of neural mechanisms that, when perturbed, manifest as night time disorders of sleep. These "night time" disorders are often accompanied by "daytime" symptoms such as fatigue, hypersomnolence, executive dysfunction, and impaired response to stress. Integrating both basic- and clinical-science approaches we are able to explore these critical neurological disorders.
Awards and Honors
Scn1a dysfunction alters behavior but not the effect of stress on seizure response. Genes Brain Behav. 2016 Mar;15(3):335-47.
Elevated serotonergic signaling amplifies synaptic noise and facilities the emergence of epileptiform network oscillations. J Neurophysiol. 2014; 112(10):2357-73.
Altered sleep regulation in a mouse model of SCN1A-derived genetic epilepsy with febrile seizures plus (GEFS+). Epilepsia. 2013;54(4):625-34.
- CDC Podcast: Recognizing Symptoms for Sleep Disorders
- CDC Press Release: Undiagnosed Sleep Problems May Lead To Long Term Health Issues
- WebMD: The Best Mattress for a Better Night’s Sleep
- The Signs (and Dangers) of a Sleepy Nurse
- Shift Work Sleep Disorder: The role of the Nurse
- Lack of Sleep Contributing to Obesity