Nicole Steinmetz, PhD

Professor
Department of Biomedical Engineering
Case School of Engineering
School of Medicine
Assistant Professor
Department of Radiology
School of Medicine
Associate Professor
Department of Materials Science and Engineering
Case School of Engineering
Associate Professor
Department of Macromolecular Science and Engineering
Case School of Engineering
Member
Cancer Imaging Program
Case Comprehensive Cancer Center

Research Information

Research Interests

  • Medical research
  • Bio-inspired materials science
  • Plant virus-based nanoparticles
  • Nanomaterials
  • Drug delivery
  • MRI contrast agents
  • Targeted therapeutics
  • Immunotherapies
  • Breast, prostate, ovarian and colon cancer
  • Cardiovascular disease

Awards and Honors

Mt. Sinai Scholar
2011
Case Western Reserve University
AHA and NIH Postdoctoral Fellow
2010
The Scripps Research Institute
Postdoctoral Fellow
2009
American Heart Association
AHA and NIH Postdoctoral Fellow
2009
The Scripps Research Institute
NIH/NIBIB Pathway to Independence Grant
2009
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
AHA and NIH Postdoctoral Fellow
2008
The Scripps Research Institute
Postdoctoral Fellow
2008
American Heart Association
Marie Curie Early Stage Training Fellowship
2007
European Commission
AHA and NIH Postdoctoral Fellow
2007
The Scripps Research Institute
Marie Curie Early Stage Training Fellowship
2006
European Commission
Marie Curie Early Stage Training Fellowship
2005
European Commission
Marie Curie Early Stage Training Fellowship
2004
European Commission

External Appointments

  • Session Chair, Protein and Viral Nanoparticle Track, FNANO, current
  • Editorial Board Member, Wiley Interdisciplinary Reviews (WIREs), current
  • Advisory Editorial Board Member, ACS journal, Molecular Pharmaceutics, current
  • Chair, Gordon Conference of Physical Virology, 2015

Publications

View All Publications

Design rules for nanomedical engineering: from physical virology to the applications of virus-based materials in medicine. J Biol Phys. 2013 Mar;39(2):301-25. doi: 10.1007/s10867-013-9314-z. Epub 2013 Apr 19.

Interior engineering of a viral nanoparticle and its tumor homing properties. Biomacromolecules. 2012 Dec 10;13(12):3990-4001. doi: 10.1021/bm301278f. Epub 2012 Nov 14.

Infusion of imaging and therapeutic molecules into the plant virus-based carrier cowpea mosaic virus: cargo-loading and in vitro delivery. J Control Release. 2013 Dec 10;172(2):568-78. doi: 10.1016/j.jconrel.2013.04.023. Epub 2013 May 9.

Increased tumor homing and tissue penetration of the filamentous plant viral nanoparticle potato virus X. Mol Pharm. 2013 Jan 7;10(1):33-42. doi: 10.1021/mp300240m. Epub 2012 Jul 9.

Intravital Imaging of Human Prostate Cancer Using Viral Nanoparticles Targeted to Gastrin-Releasing Peptide Receptors. Small. 2011 Jun 20;7(12):1664-72. doi: 10.1002/smll.201000435. Epub 2011 Apr 26. *Cover article

Education

Doctor of Philosophy
Bionanotechnology
John Innes Centre, UK
2007
Master of Science
Molecular Biotechnology
RWTH-Aachen University, Germany
2004