Doris Duke - TB/HIV Case Finding

Community-Based Case Finding of TB-HIV Patients in Kampala, Uganda

Information:

Sponsor - Doris Duke Charitable Foundation, USA
Principal Investigator - Christopher C. Whalen, M.D., M.S., University of Georgia and CWRU

Type of Study House-to-House Prevalence Survey
Design Cross-Sectional
Project Site Rubaga Division in Kampala, Uganda
Sample Size 5,000 per year for two years
Population Adults (≥ 15 years old)
Study Period 2007-2009
Interactions Collaborating investigators and staff and utilizing shared project management infrastructure

Goal of Study:

The goal is to determine the effectiveness of community-based screening approaches for HIV-associated TB using chronic cough (cough > 2 weeks) as a screening tool among community households and household contacts of index TB cases.

Objectives of Study:

  1. To determine the effectiveness of community-based screening for HIV-associated TB using chronic cough (cough > 2 weeks) as a screening tool
  2. To determine the effectiveness of screening for HIV-associated TB among household contact of infectious TB cases
  3. To compare clinical outcomes between patients identified through the community-based screening and the household based screening approaches