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School of Medicine

From driving cutting-edge research to bringing medical innovations to market, landing competitive awards and more, the faculty, staff and students at Case Western Reserve University School of Medicine know how to make headlines.

Recent News

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Case Western Reserve/University Hospitals researcher part of elite trans-Atlantic network to study “molecular switch” that contributes to heart disease
Paris-based foundation supports effort to potentially “turn off” vascular problems Transcription factors are proteins that determine whether specific genes are transcribed or not by binding to DNA. In other words, they help turn genes "on" or "off." One such transcription factor, Kruppel-like…
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Database funded to help researchers understand the effect of bipolar disorder throughout adult life span
Research aims to assist patients and caregivers’ plan care choices Not much is known about how bipolar disorder (BD) affects people throughout their lives. Do women and men differ in the severity of their symptoms? Does a person’s age when a bipolar diagnosis is made have any bearing on how severe…
Blood Cells Could Hold Master Clock Behind Aging
Blood cells could hold the key to aging, according to new research out of Case Western Reserve University School of Medicine. In a study published in Aging Cell, researchers found human blood cells have an intrinsic clock that remains steady even after transplant. The researchers say the clock…
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New images show serotonin activating its receptor for first time
High-tech microscope reveals receptor in action, with focus on drug development Serotonin (3A) receptors are common drug targets in the treatment of pain, gastrointestinal dysfunctions, and mood disorders, yet little is known about their three-dimensional structure. Details about serotonin receptor…
Transition into Our New Home
It was just a few days ago that the University was closed due to the severe cold, followed by 60 degree weather making it feel like spring. We are told to prepare for another cold snap in a week or so and will once again need to reach into the closet for the long underwear, down coat, and high…
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Case Comprehensive Cancer Center receives $3.2M NIH grant for health disparities research
Two projects focus on racial disparities in colorectal and breast cancer The Case Comprehensive Cancer Center received a three-year, nearly $3.2 million grant from the National Cancer Institute to investigate colorectal and breast cancer health disparities. The grant is one of only four Specialized…
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Researchers Develop New Approach for Vanquishing Superbugs
A scientific team from Case Western Reserve University School of Medicine and Cleveland Clinic has developed a new way to identify second-line antibiotics that may be effective in killing germs already resistant to a first-line antibiotic – potentially helping overcome antibiotic resistance. This…
New Skin Test Detects Prion Infection Before Symptoms Appear
Microscopic examination of brain tissues of prion-infected animals. (Left) Staining shows spongiform degeneration. (Right) Staining shows intense misfolded prion protein. Prions can infect both humans and animals, causing Creutzfeldt-Jakob disease (CJD) in humans, mad cow disease in…
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MLK Day
Monday is Martin Luther King Day in America. Though much has improved in our country for African Americans since his tragic assassination in 1968 – the year that so much changed – we still live in a world where serious health disparities persist, and we have too few tools to combat them. As Dr.…
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Case Western Reserve researchers cure drug-resistant infections without antibiotics
Results in mouse sepsis model lay foundation for clinical trials Biochemists, microbiologists, drug discovery experts and infectious disease doctors have teamed up in a new study that shows antibiotics are not always necessary to cure sepsis in mice. Instead of killing causative bacteria with…