School of Medicine

When sports fans in Northeast Ohio were on edge through the Cleveland Cavaliers’ championship run last June, second-year medical student Ann Xing was right along with them—in the front row. Xing reported on the Cavs through the 2015-16 season for the popular Chinese TV network LeSports, and…

Researchers have known that part of the challenge in treating penicillin-resistant infections lies in understanding the way bacteria inactivate penicillin antibiotics. The enzymes that do this, beta-lactamases, chop up the antibiotics rendering them useless. One particularly problematic group of…

Specific cells in the retina trigger inflammation and vision impairment associated with diabetes, according to new research out of Case Western Reserve University School of Medicine. The findings unexpectedly implicate Mu¨ller cells—which provide structural support in the retina—as key drivers of…

Genetic mutations can increase a person's cancer risk, but other gene "enhancer" elements may also be responsible for disease progression, according to new research out of the Case Comprehensive Cancer Center. In a breakthrough study published in Nature Communications, scientists discovered changes…

The running joke in Alex Huang’s pediatric oncology immunotherapy lab is that, to become a member of the research team, you have to shave your head. While that’s not really the case, many do so anyway—for a good cause. The researchers in Huang’s lab will “brave the shave” once again at the 2017…

Investigational drug may help combat this serious global health threat The deadly fungus, Candida auris, which has been found in hospitals, is resistant to entire classes of antimicrobial drugs, limiting treatment options for those infected. First reported in 2009, the fungus has been linked to…

Since the discovery of penicillin in 1928, antibiotics have made the world a much safer and healthier place. But Shakespeare was onto something when he asked if it’s possible to have too much of a good thing. In the case of antibiotics, the answer is increasingly “yes.” As a result, Case Western…

An enzyme that helps break down cholesterol may also be a therapeutic target to stave off neurologic diseases, including Alzheimer’s and a rare genetic disorder, according to a new study published in the Journal of Biological Chemistry. Researchers from Case Western Reserve University School of…

New national study suggests communities are growing source of infection The adage that kids are growing up too fast these days has yet another locus of applicability. In a new, first-of-its-kind study, researchers from Case Western Reserve University School of Medicine have found a 700-percent…

Krzysztof Palczewski is a visionary—in some cases, literally. Renowned for breakthroughs that expanded our understanding of how the eye functions, he has conducted research that illuminates pathways to stop and even reverse degenerative conditions that can lead to blindness. A member of the Case…