Malignant tissue removed during surgeries is frozen, sectioned into thin slices, stained, imaged with a microscope (2D images), and assessed by pathologists to provide intraoperative consultations. The frozen section procedure is lengthy, slows down surgeries, inflicts extra operating room cost, and is less accurate than permanent sections. Here, we will develop a product that quickly prepares the tissue and enables 3D visualization of the tissue, potentially saving time, money, and lives.
- Y. Liu, M. C. G. Broberg, M. Watanabe, A. M. Rollins, M. W. Jenkins, SLIME: robust, high-speed 3D microvascular mapping," Sci Rep. 2019 Jan 29;9(1):893. doi: 10.1038/s41598-018-37313-z.
- B. J. Blackburn, S. Gu, M. R. Ford, V. de Stefano, M. W. Jenkins, W. J. Dupps, A. M. Rollins, "Noninvasive assessment of corneal crosslinking with phase-correlation optical coherence tomography," Invest Opthalmol Vis Sci. 2019 Jan 2;60(1):41-51. doi: 10.1167/iovs.18-25535
- O.U. Kilinc, X. Zhao, M. W. Jenkins, C. S. Snyder, A. M. Rollins, "Imaging of the atrioventricular nodal conduction tissue in porcine hearts using optical coherence tomography," J Innov Cardiac Rhythm Management 2019 accepted
- M. Ganguly, M. W. Jenkins, E. D. Jansen, H. J. Chiel, "Thermal block of action potentials is primarily due to voltage-dependent potassium currents," J Neural Eng 2019 accepted
- B. J. Blackburn, M. W. Jenkins, A. M. Rollins, B. J. Dupps, "A review of structural and biomechanical changes in the cornea in aging, disease and photochemical crosslinking," Frontiers in Science Research 2019 accepted