Biomedical Imaging

Case Western Reserve University is a world leader in developing novel biomedical imaging technologies for translational and basic science applications. Research programs in imaging serve as the cornerstones for numerous interdisciplinary programs, including cancer diagnosis and prognosis, gene therapy, nanotechnology and drug delivery, cardiac physiology and understanding of metabolic diseases. 

Our imaging program collaborates extensively with biomedical research programs in the Case School of Medicine, University Hospitals and Cleveland Clinic, resulting in rapid translation of imaging technologies developed here to the patient bedside and scientists’ bench-side. Our major research thrusts include developing and optimizing novel imaging technologies, creating new capabilities for existing imaging systems and applying novel imaging technologies to clinical and preclinical investigations. These areas include:

Imaging Technology – Innovation of image acquisition and reconstruction technologies for faster image acquisition, higher spatial resolution and more comprehensive evaluation of anatomic structure and physiological functions. 

Computational Algorithms – New computational imaging analysis tools to identify subtle sub-visual cues that can enable predictions of disease behavior and progression, as well as lead to innovative developments in imaging quality.

Imaging-Guided Interventions – Development of new and integrated devices and imaging technologies to provide real-time, imaging-guided surgery, neuromodulation and other interventions.

Molecular Imaging – Development of new imaging contrast agents that provide imaging biomarkers and molecular details of disease progression, better delineation of tumor margins and more sensitive detection of tumor metastasis.

Affiliated Labs and Centers 

Faculty

  • James Basilion headshot

    James P. Basilion, PhD

    Professor
    Department of Biomedical Engineering
    Department of Radiology
    Case School of Engineering, School of Medicine
    Co-Leader
    Cancer Imaging Program
    Case Comprehensive Cancer Center

    Email: james.basilion@case.edu

    Phone: 216.983.3264

  • Rui Cao

    Rui Cao, PhD

    Assistant Professor
    Department of Biomedical Engineering
    Case School of Engineering, School of Medicine

    Email: ruicao@case.edu

  • William Grissom

    William Grissom, PhD

    Professor
    Department of Biomedical Engineering
    Case School of Engineering, School of Medicine
    Member
    Cancer Imaging Program
    Case Comprehensive Cancer Center

    Email: wag57@case.edu

  • Michael Jenkins

    Michael Jenkins, PhD

    Associate Professor
    Biomedical Engineering
    Case School of Engineering, School of Medicine
    Member
    Cancer Imaging Program
    Case Comprehensive Cancer Center

    Email: michael.jenkins@case.edu

  • Karathanasis

    Efstathios (Stathis) Karathanasis, PhD

    Associate Chair
    Department of Biomedical Engineering
    School of Medicine
    Professor
    Department of Biomedical Engineering
    Case School of Engineering, School of Medicine
    Member
    Cancer Imaging Program
    Case Comprehensive Cancer Center

    Email: efstathios.karathanasis@case.edu

    Phone: 216.368.4617

  • Shuo Li headshot

    Shuo Li, PhD

    Professor
    Biomedical Engineering
    Case School of Engineering, School of Medicine
    Professor
    Computer Data Science
    Case School of Engineering
    Member
    Cancer Imaging Program
    Case Comprehensive Cancer Center

    Email: shuo.li11@case.edu

  • Zheng Rong Lu headshot

    Zheng-Rong Lu, PhD

    Professor
    Department of Biomedical Engineering
    Case School of Engineering, School of Medicine
    M. Frank Rudy and Margaret Domiter Rudy Professor of Biomedical Engineering
    Member
    Cancer Imaging Program
    Case Comprehensive Cancer Center

    Email: zheng-rong.lu@case.edu

    Phone: 216.368.0187

  • Dan_Ma_Dec2021

    Dan Ma, PhD

    Associate Professor
    Department of Biomedical Engineering
    Case School of Engineering, School of Medicine
    Member
    Cancer Imaging Program
    Case Comprehensive Cancer Center

    Email: dan.ma@case.edu

    Phone: 216.844.5935

  • Debra McGivney

    Debra McGivney, PhD

    Assistant Professor
    Department of Biomedical Engineering
    Case School of Engineering, School of Medicine

    Email: debra.mcgivney@case.edu

    Phone: 216.368.6248

  • Christopher Nguyen

    Christopher Nguyen

    Director, Cardiovascular Innovation Research Center

  • andrew_rollins

    Andrew Rollins, PhD

    Professor
    Department of Biomedical Engineering
    Case School of Engineering, School of Medicine
    Member
    Cancer Imaging Program
    Case Comprehensive Cancer Center

    Email: andrew.rollins@case.edu

    Phone: 216.368.1917

  • Satish Viswanath

    Satish E. Viswanath, PhD

    Associate Professor
    Department of Biomedical Engineering
    Case School of Engineering, School of Medicine
    Associate Professor
    Department of Radiology
    School of Medicine
    Associate Professor
    Department of Electrical, Computer, and Systems Engineering
    Case School of Engineering
    Member
    Cancer Imaging Program
    Case Comprehensive Cancer Center
    Co-Leader
    CCCC Machine Learning Working Group
    Co-Director
    Center for AI Enabling Discovery in Disease Biology (AID2B)
    School of Medicine

    Email: satish.viswanath@case.edu

    Phone: 216.368.3888

  • Image of headshot of David Wilson

    David L. Wilson, PhD

    Robert J. Herbold Professor of Biomedical Engineering
    Department of Biomedical Engineering
    Case School of Engineering, School of Medicine
    Professor
    Department of Radiology
    School of Medicine
    Member
    Cancer Imaging Program
    Case Comprehensive Cancer Center

    Email: david.wilson@case.edu

    Phone: 216.368.4099

  • Image of headshot of Xin Yu

    Xin Yu, ScD

    F. Alex Nason Professor II of Biomedical Engineering
    Department of Biomedical Engineering
    Case School of Engineering, School of Medicine
    Professor
    Department of Physiology and Biophysics
    School of Medicine
    Professor
    Department of Radiology
    School of Medicine

    Email: xin.yu@case.edu

    Phone: 216.368.3918

  • Mei Zhang

    Mei Zhang, PhD

    Assistant Professor
    Department of Biomedical Engineering
    Case School of Engineering
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: mei.zhang2@case.edu

    Phone: 216.844.3098

  • Labhasetwar

    Vinod Labhasetwar

    Professor, Cleveland Clinic Lerner College of Medicine

    Email: labhasv@ccf.org

Research Faculty

Affiliated Associated Faculty

  • Agata Exner headshot

    Agata A. Exner, PhD

    Vice Chair of Basic Research
    Department of Radiology
    School of Medicine
    Professor
    Department of Radiology
    School of Medicine
    Professor
    Department of Biomedical Engineering
    Case School of Engineering
    Co-Leader
    Cancer Imaging Program
    Case Comprehensive Cancer Center
    Associate Director
    Medical Scientist Training Program
    School of Medicine
    Director
    CWRU Center for Imaging Research

    Email: agata.exner@case.edu

    Phone: 216.368.6727

  • Portrait of Chris Flask

    Chris A. Flask, PhD

    Professor
    Department of Radiology
    Pediatrics
    Biomedical Engineering
    School of Medicine
    Co-Director
    Imaging Research Core
    School of Medicine
    Member
    Cancer Imaging Program
    Case Comprehensive Cancer Center

    Email: christopher.flask@case.edu

    Phone: 216.844.4963

  • Mark Griswold, PhD

    Mark Griswold, PhD

    Professor
    Department of Radiology
    School of Medicine
    Professor
    Department of Biomedical Engineering
    Case School of Engineering
    Member
    Cancer Imaging Program
    Case Comprehensive Cancer Center

    Email: mark.griswold@case.edu

    Phone: 216.844.8085

  • Zhenghong Lee headshot

    Zhenghong Lee, PhD

    Professor
    Department of Radiology
    School of Medicine
    Associate Professor
    Department of Biomedical Engineering
    Case School of Engineering
    Co-Leader
    Cancer Imaging Program
    Case Comprehensive Cancer Center

    Email: zhenghong.lee@case.edu

    Phone: 216.844.7920

  • Headshot of CWRU Professor Raymond Muzic

    Raymond F. Muzic, Jr., PhD

    Professor
    Department of Radiology
    School of Medicine
    Professor
    Department of Biomedical Engineering
    Case School of Engineering
    Scientific Director
    Quantitative Imaging Laboratory
    School of Medicine
    Member
    Cancer Imaging Program
    Case Comprehensive Cancer Center

    Email: raymond.muzic@case.edu

    Phone: 216.368.0727