Biomedical Imaging

Case Western Reserve University is a world leader in developing novel biomedical imaging technologies for translational and basic science applications. Research programs in imaging serve as the cornerstones for numerous interdisciplinary programs, including cancer diagnosis and prognosis, gene therapy, nanotechnology and drug delivery, cardiac physiology and understanding of metabolic diseases. 

Our imaging program collaborates extensively with biomedical research programs in the CWRU School of Medicine, University Hospitals and Cleveland Clinic, resulting in rapid translation of imaging technologies developed here to the patient bedside and scientists’ bench-side. Our major research thrusts include developing and optimizing novel imaging technologies, creating new capabilities for existing imaging systems and applying novel imaging technologies to clinical and preclinical investigations. These areas include:

Imaging Technology

Innovation of image acquisition and reconstruction technologies for faster image acquisition, higher spatial resolution and more comprehensive evaluation of anatomic structure and physiological functions. 

Imaging-guided Interventions

Development of new and integrated devices and imaging technologies to provide real-time, imaging-guided surgery, neuromodulation and other interventions.

Molecular Imaging

Development of new imaging contrast agents that provide imaging biomarkers and molecular details of disease progression, better delineation of tumor margins and more sensitive detection of tumor metastasis.

Medical Imaging AI

Machine and deep learning algorithms are used for the diagnosis and staging of disease (e.g., oncological, cardiovascular, digestive, genitourinary, among others) from imaging exams, including CT, MRI, digital pathology, and multiplex imaging. Advanced computational techniques for virtual contrast, reconstruction, enhancement, multimodal integration.

Affiliated Centers and Core Facilities 

• Biomedical Imaging Laboratory (BMIL)
• Cancer Imaging Program of the Case Comprehensive Cancer Center
• Center for Biomolecular Engineering 
• CWRU Center for Imaging Research (CCIR)
• The Center for AI Enabling Discovery in Disease Biology (AID2B) 
• Laboratory for Cancer Nanotechnology and Immunotherapy 
• Immunoengineering Lab 
• Epilepsy Center
• Imaging Research Core
• School of Medicine Light Microscopy Imaging Core (SOM-LMIC) 

Faculty

Research Faculty

Associated Faculty