Senior Research Associate
Department of Biomedical Engineering
Case School of Engineering
School of Medicine
Member
Cancer Imaging Program
Case Comprehensive Cancer Center
Develops imaging agent for detection and photodynamic therapy of cancer cells and tissue that would allow the surgeon to decide in real time how aggressive the surgical intervention need be.
Research Information
Research Interests
Multidisciplinary areas of molecular imaging, immune-mediated inflammatory responses, cancer immunology, cell signaling and cancer stem cells as well as nutrition, radiation-induced thyroid autoimmunity, and clinical pediatric immunology.
Publications
- Walker, E., Turaga, S., Wang, X., Ramamurthy, G., Shukla, S., Basilion, J., & Lathia, J. (2021). Development of Near-Infrared Imaging Agents for Detection of Junction Adhesion-Molecule A Protein.. Translational Oncology, 14 (3), 101007.
- Wang, X., Shirke, A., Walker, E., Sun, R., Ramamurthy, G., Wang, J., Shan, L., Mangadlao, J., Dong, Z., Wang, Z., Liu, H., Schluchter, M., Luo, D., Wang, Y., Stauffer, S., Brady-Kalnay, S., Hoimes, C., Lee, Z., & Basilion, J. (2021). Small-Molecule-Based Prodrug Targeting Prostate Specific Membrane Antigen for the Treatment of Prostate Cancer.. Cancers, 13 (3), 417.
- Luo, D., Wang, X., Walker, E., Wang, J., Springer, S., Lou, J., Ramamurthy, G., Burda, C., & Basilion, J. (2020). Nanoparticle Yield Increased Drug Uptake and Therapeutic Efficacy Upon Sequential Near-Infrared Irradiation. ACS Nano, 14 , 15193-15203.
- Walker, E., Liu, Y., Kim, S., Biro, M., Iyer, N., Ezaldein , H., Scott, J., Merati, M., Mistur , R., Zhou, B., Straight, B., Yim, J., Bogyo, M., Crescimanno, M., Wilson, D. L., Basilion, J. L., & Popkin, D. L. (2020). A Protease-Activated Fluorescent Probe Allows Rapid Visualization of Keratinocyte Carcinoma during Excision.. Cancer research.
- Walker, E., Ramamurthy, ., Shirke, A., Mangadlao , J., Wang, Z., & Basilion, J. (2019). Photodynamic Therapy as an Effective Adjuvant After Image-Guided Surgery of Prostate Tumor. Cancer Research.
- Walker, E., Iyer, S., Biro, M., Kim, I., Zhou, B., Bogyo, M., Basilion, J., Popkin, D., & Wilson, D. (2019). Molecular Imaging and Validation of Margins in Surgically Excised Nonmelanoma Skin Cancer Specimens. Journal of Molecular Imaging.
- Liu, Y., Walker, E., Iyer, N., Biro, M., Kim, S., Zhou, B., Straight, B., Bogyo, M., Basilion, J., Popkin, D., & Wilson, D. L. (2019). Molecular imaging and validation of margins in surgically excised nonmelanoma skin cancer specimens.. Journal of medical imaging (Bellingham, Wash.), 6 (1), 016001.
- Liu, Y., Walker, E., Iyer, N., Biro, M., Kim, S., Zhou, B., Straight, B., Bogyo, M., Basilion, J., Popkin, D., & Wilson, D. L. (2019). Molecular imaging and validation of margins in surgically excised nonmelanoma skin cancer specimens.. Journal of medical imaging (Bellingham, Wash.), 6 (1), 016001.
- Walker, E., Shukla, S., & Gupta, S. (2018). Acquisition of tumorigenic potential and therapeutic resistance in CD133+ subpopulation of prostate cancer cells exhibiting stem-cell like characteristics. Cancer Letters, 430 , 25-33.
- Walker, E., Mann, M., Honda, K., Vidimos, A., Schluchter, M., Straight, B., Bogyo, M., Popkin, D., & Basilion, J. (2017). Rapid Visualization of nonmelanoma skin cancer. Journal Am. Acad. Dermatolorgy, 76 (2), 209-216.e9.
- Walker, E., Basilion, J., Gopalakrishnan , R., & Bogyo, M. (2014). Microscopic detection of quenched activity based optical imaging probes using an antibody detection system: localizing protease activity. Molecular Imaging and Biology, 5 , 608-618.