Area of Tissue Changes.

Relative areas showing tissue changes in the implanted muscles.
In ‘Controls’ electrode was left in situ.

Electrode Cleaning
(At Left) Scanning electron micrograph of the insulated coil section from an as-packed NEC electrode, showing adherent particulate material on the surface.

(At Right) Scanning electron micrograph of the insulated coil section from a NEC electrode cleaned by a standard protocol used for the other electrodes.

(Top) Tissue from control muscle after 7 days of electrode implantation; section at level of the barb. Right: magnified view of tissue between the barb and coil (H & E stain).

(Below) Tissue from muscle in which a cleaned NEC electrode had been implanted 7 days previously. Right: shows a much more narrow zone of cellular infiltrate when compared to Top Figure which showed an as-packed electrode implanted for the same period of time.