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Rajagopalan Lab Publications

Browse publications out of the Rajagopalan Lab at Case Western Reserve University.  

  1. The NIEHS TaRGET II Consortium and environmental epigenomics. Wang T, Pehrsson EC, Purushotham D, Li D, Zhuo X, Zhang B, Lawson HA, Province MA, Krapp C, Lan Y, Coarfa C, Katz TA, Tang WY, Wang Z, Biswal S, Rajagopalan S, Colacino JA, Tsai ZT, Sartor MA, Neier K, Dolinoy DC, Pinto J, Hamanaka RB, Mutlu GM, Patisaul HB, Aylor DL, Crawford GE, Wiltshire T, Chadwick LH, Duncan CG, Garton AE, McAllister KA; TaRGET II Consortium, Bartolomei MS, Walker CL, Tyson FL. Nat Biotechnol. 2018 Mar 6;36(3):225-227. doi: 10.1038/nbt.4099.
  2. Short-Term Blood Pressure Responses to Ambient Fine Particulate Matter Exposures at the Extremes of Global Air Pollution Concentrations. Huang W, Wang L, Li J, Liu M, Xu H, Liu S, Chen J, Zhang Y, Morishita M, Bard RL, Harkema JR, Rajagopalan S, Brook RD. Am J Hypertens. 2018 Feb 2. doi: 10.1093/ajh/hpx216. [Epub ahead of print] PMID: 29409056
  3. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults. A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Brook RD, Rajagopalan S.J Am Soc Hypertens. 2018 Mar;12(3) PMID: 29396104
  4. Exercise-Induced Pulmonary Hypertension: Translating Pathophysiological Concepts Into Clinical Practice. Naeije R, Saggar R, Badesch D, Rajagopalan S, Gargani L, Rischard F, Ferrara F, Marra AM, D' Alto M, Bull TM, Saggar R, Grünig E, Bossone E.Chest. 2018 Jan 31. pii: S0012-3692(18)30161-2. doi: 10.1016/j.chest.2018.01.022. PMID: 29382472
  5. CITED2 restrains pro-inflammatory macrophage activation and response. Kim GD, Das R, Rao X, Zhong J, Deiuliis JA, Ramirez-Bergeron DL, Rajagopalan S, Mahabeleshwar GH. Mol Cell Biol. 2017 Dec 4. pii: MCB.00452-17. doi: 10.1128/MCB.00452-17. PMID: 29203644
  6. Noncoding RNAs in Cardiovascular Disease: Pathological Relevance and Emerging Role as Biomarkers and Therapeutics. Gangwar RS, Rajagopalan S, Natarajan R, Deiuliis JA. Am J Hypertens. 2018 Jan 12;31 PMID: 29186297
  7. Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes. Rajagopalan S, Brook R. N Engl J Med. 2017 Nov 23;377(21):2098-9.No abstract available.  PMID: 29182250
  8. Inhalation Exposure to PM2.5 Counteracts Hepatic Steatosis in Mice Fed High-fat Diet by Stimulating Hepatic Autophagy. Qiu Y, Zheng Z, Kim H, Yang Z, Zhang G, Shi X, Sun F, Peng C, Ding Y, Wang A, Chen LC, Rajagopalan S, Sun Q, Zhang K. Sci Rep. 2017 Nov 24;7(1):16286. doi: 10.1038/s41598-017-16490-3. PMID: 29176715 Free PMC Article
  9. Monocyte DPP4 Expression in Human Atherosclerosis Is Associated With Obesity and Dyslipidemia. Rao X, Deiuliis JA, Mihai G, Varghese J, Xia C, Frieman MB, Sztalryd C, Sun XJ, Quon MJ, Taylor SI, Rajagopalan S, Zhong J.Diabetes Care. 2018 Jan;41(1)Epub 2017 Nov 10. PMID: 29127241
  10. Effect of Particulate Matter Air Pollution on Cardiovascular Oxidative Stress Pathways. Rao X, Zhong J, Brook RD, Rajagopalan S. Antioxid Redox Signal. 2018 Mar 20;28(9):797-818. Epub 2017 Dec 12. PMID: 29084451
  11. Extreme levels of ambient air pollution adversely impact cardiac and central aortic hemodynamics: the AIRCMD-China study. Liu S, Brook RD, Huang W, Fan Z, Xu H, Wu R, Sun Z, Zhao X, Ruan Y, Yan J, Sun L, Liang R, Lian H, Gu D, Rajagopalan S. J Am Soc Hypertens. 2017 Nov;11(11):754-761.e3. doi: 10.1016/j.jash.2017.09.009. Epub 2017 Sep 28. PMID: 29031802
  12. The Role of the Mineralocorticoid Receptor in Inflammation: Focus on Kidney and Vasculature. Belden Z, Deiuliis JA, Dobre M, Rajagopalan S. Am J Nephrol. 2017;46(4):298-314.  Epub 2017 Oct 10. PMID: 29017166
  13. Personal-level exposure to environmental temperature is a superior predictor of endothelial-dependent vasodilatation than outdoor-ambient level. Ejike C, Wang L, Liu M, Wang W, Morishita M, Bard RL, Huang W, Harkema J, Rajagopalan S, Brook RD. J Am Soc Hypertens. 2017 Nov;11(11):746-753.e1.  Epub 2017 Sep 28. PMID: 28989070
  14. Cardiovascular evaluation and management of iron overload cardiomyopathy in sickle cell disease. Ginwalla M, AlMasoud A, Tofovic D, Alin T, Al-Kindi S, Oliveira G, Rajagopalan S, Schilz R, Little J. Am J Hematol. 2018 Jan;93(1)Epub 2017 Oct 23.  PMID: 28971490
  15. Design of the exercise MRI evaluation of HIV-pulmonary arterial hypertension longitudinal determinants (EXALTED) trial. Alaiti MA, Goud A, Ramani G, Bagchi S, Al-Kindi S, Sawicki S, Longenecker C, Jenkins T, Pauza D, Park M, McComsey G, Simonetti O, Hoit B, Rajagopalan S. J Cardiovasc Med (Hagerstown). 2017 Nov;18(11):888-896. PMID: 28937582
  16. Stressed About Air Pollution: Time for Personal Action. Brook RD, Rajagopalan S. Circulation. 2017 Aug 15;136(7):628-631.   PMID: 28808145
  17. Cancer risks of anti-hyperglycemic drugs for type 2 diabetes treatment - a clinical appraisal. Vora J, Ray K, Kosiborod M, Poulter NR, Rajagopalan S, Leiter LA. J Diabetes Complications. 2017 Sep;31(9):1451-1457. Epub 2017 Jun 15. Review. PMID: 28655490
  18. Air Pollution and Cardiometabolic Disease: An Update and Call for Clinical Trials. Brook RD, Newby DE, Rajagopalan S. Am J Hypertens. 2017 Dec 8;31(1):1-10. doi: 10.1093/ajh/hpx109. PMID: 28655143
  19. The regulatory role of DPP4 in atherosclerotic disease. Duan L, Rao X, Xia C, Rajagopalan S, Zhong J. Cardiovasc Diabetol. 2017 Jun 15;16(1):76. Review. PMID: 28619058 Free PMC Article
  20. Design of the Magnetic Resonance Imaging Evaluation of Mineralocorticoid Receptor Antagonism in Diabetic Atherosclerosis (MAGMA) Trial. Rajagopalan S, Alaiti MA, Broadwater K, Goud A, Gaztanaga J, Connelly K, Fares A, Shirazian S, Kreatsoulas C, Farkouh M, Dobre M, Fink JC, Weir MR. Clin Cardiol. 2017 Sep;40(9) Epub 2017 May 26.