Aggrecan accumulates at sites of increased pulmonary arterial pressure in idiopathic pulmonary arterial hypertension
Oscar van der Have, Timothy J Mead, Christian Westöö, Niccolò Peruzzi, Ayse C Mutgan, Christian Norvik, Martin Bech, André Struglics, Konrad Hoetzenecker, Hans Brunnström, Gunilla Westergren-Thorsson, Grazyna Kwapiszewska, Suneel S Apte, Karin Tran-Lundmark | pmid:36824691
Pulmonary circulation | February 24, 2023
ADAMTS6: Emerging roles in cardiovascular, musculoskeletal and cancer biology
Timothy J Mead | pmid:36339722
Frontiers in molecular biosciences | November 7, 2022
Proteolysis: a key post-translational modification regulating proteoglycans
Timothy J Mead, Sumit Bhutada, Daniel R Martin, Suneel S Apte | pmid:35785985
American journal of physiology. Cell physiology | July 5, 2022
Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development
Timothy J Mead, Daniel R Martin, Lauren W Wang, Stuart A Cain, Cagri Gulec, Elisabeth Cahill, Joseph Mauch, Dieter Reinhardt, Cecilia Lo, Clair Baldock, Suneel S Apte | pmid:35503090
eLife | May 3, 2022
ADAMTSL5 is an epigenetically activated gene underlying tumorigenesis and drug resistance in hepatocellular carcinoma
Maria Arechederra, Sehrish K Bazai, Ahmed Abdouni, Celia Sequera, Timothy J Mead, Sylvie Richelme, Fabrice Daian, Stéphane Audebert, Rosanna Dono, Anthony Lozano, Damien Gregoire, Urszula Hibner, Daniela S Allende, Suneel S Apte, Flavio Maina | pmid:33197513
Journal of hepatology | November 16, 2020
The secreted protease Adamts18 links hormone action to activation of the mammary stem cell niche
Dalya Ataca, Patrick Aouad, Céline Constantin, Csaba Laszlo, Manfred Beleut, Marie Shamseddin, Renuga Devi Rajaram, Rachel Jeitziner, Timothy J Mead, Marian Caikovski, Philipp Bucher, Giovanna Ambrosini, Suneel S Apte, Cathrin Brisken | pmid:32218432
Nature communications | March 29, 2020
Visualization and Quantification of Pericellular Matrix
Timothy J Mead, Suneel S Apte | pmid:31463918
Methods in molecular biology (Clifton, N.J.) | August 30, 2019
Alizarin Red and Alcian Blue Preparations to Visualize the Skeleton
Timothy J Mead | pmid:31463914
Methods in molecular biology (Clifton, N.J.) | August 30, 2019
Expression Analysis by RNAscope™ In Situ Hybridization
Timothy J Mead, Suneel S Apte | pmid:31463911
Methods in molecular biology (Clifton, N.J.) | August 30, 2019
Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage
Lauren W Wang, Wendy E Kutz, Timothy J Mead, Lauren C Beene, Shweta Singh, Michael W Jenkins, Dieter P Reinhardt, Suneel S Apte | pmid:30201140
Matrix biology : journal of the International Society for Matrix Biology | September 12, 2018
Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6
Bram P Prins, Timothy J Mead, Jennifer A Brody, Gardar Sveinbjornsson, Ioanna Ntalla, Nathan A Bihlmeyer, Marten van den Berg, Jette Bork-Jensen, Stefania Cappellani, Stefan Van Duijvenboden, Nikolai T Klena, George C Gabriel, Xiaoqin Liu, Cagri Gulec, Niels Grarup, Jeffrey Haessler, Leanne M Hall, Annamaria Iorio, Aaron Isaacs, Ruifang Li-Gao, Honghuang Lin, Ching-Ti Liu, Leo-Pekka Lyytikäinen, Jonathan Marten, Hao Mei, Martina Müller-Nurasyid, Michele Orini, Sandosh Padmanabhan, Farid Radmanesh, Julia Ramirez, Antonietta Robino, Molly Schwartz, Jessica van Setten, Albert V Smith, Niek Verweij, Helen R Warren, Stefan Weiss, Alvaro Alonso, David O Arnar, Michiel L Bots, Rudolf A de Boer, Anna F Dominiczak, Mark Eijgelsheim, Patrick T Ellinor, Xiuqing Guo, Stephan B Felix, Tamara B Harris, Caroline Hayward, Susan R Heckbert, Paul L Huang, J W Jukema, Mika Kähönen, Jan A Kors, Pier D Lambiase, Lenore J Launer, Man Li, Allan Linneberg, Christopher P Nelson, Oluf Pedersen, Marco Perez, Annette Peters, Ozren Polasek, Bruce M Psaty, Olli T Raitakari, Kenneth M Rice, Jerome I Rotter, Moritz F Sinner, Elsayed Z Soliman, Tim D Spector, Konstantin Strauch, Unnur Thorsteinsdottir, Andrew Tinker, Stella Trompet, André Uitterlinden, Ilonca Vaartjes, Peter van der Meer, Uwe Völker, Henry Völzke, Melanie Waldenberger, James G Wilson, Zhijun Xie, Folkert W Asselbergs, Marcus Dörr, Cornelia M van Duijn, Paolo Gasparini, Daniel F Gudbjartsson, Vilmundur Gudnason, Torben Hansen, Stefan Kääb, Jørgen K Kanters, Charles Kooperberg, Terho Lehtimäki, Henry J Lin, Steven A Lubitz, Dennis O Mook-Kanamori, Francesco J Conti, Christopher H Newton-Cheh, Jonathan Rosand, Igor Rudan, Nilesh J Samani, Gianfranco Sinagra, Blair H Smith, Hilma Holm, Bruno H Stricker, Sheila Ulivi, Nona Sotoodehnia, Suneel S Apte, Pim van der Harst, Kari Stefansson, Patricia B Munroe, Dan E Arking, Cecilia W Lo, Yalda Jamshidi | pmid:30012220
Genome biology | July 18, 2018
ADAMTS proteins in human disorders
Timothy J Mead, Suneel S Apte | pmid:29885460
Matrix biology : journal of the International Society for Matrix Biology | June 10, 2018
ADAMTS9-Regulated Pericellular Matrix Dynamics Governs Focal Adhesion-Dependent Smooth Muscle Differentiation
Timothy J Mead, Yaoyao Du, Courtney M Nelson, Ndeye-Aicha Gueye, Judith Drazba, Carolyn M Dancevic, Mireille Vankemmelbeke, David J Buttle, Suneel S Apte | pmid:29642006
Cell reports | April 12, 2018
The metalloproteinase-proteoglycans ADAMTS7 and ADAMTS12 provide an innate, tendon-specific protective mechanism against heterotopic ossification
Timothy J Mead, Daniel R McCulloch, Jason C Ho, Yaoyao Du, Sheila M Adams, David E Birk, Suneel S Apte | pmid:29618652
JCI insight | April 6, 2018
Massive aggrecan and versican accumulation in thoracic aortic aneurysm and dissection
Frank S Cikach, Christopher D Koch, Timothy J Mead, Josephine Galatioto, Belinda B Willard, Kelly B Emerton, Matthew J Eagleton, Eugene H Blackstone, Francesco Ramirez, Eric E Roselli, Suneel S Apte | pmid:29515038
JCI insight | March 9, 2018