Welcome to CBHI
Do you have information you would like to see posted on the CBHI web site? email firstname.lastname@example.org to receive an application.
Researchers in the Mei lab in the department of Neurosciences at CWRU have found that a gene critical to clearing up unnecessary proteins plays a role in brain development, and mutations in that gene can contribute to the pathophysiology of autism spectrum disorders and schizophrenia. The discovery, published Nov. 25 in Neuron, provides important insight into the mechanism of both disorders.
who have been awarded a five year, $3.6 million grant to develop a skin based test to diagnose Parkinson's disease by detecting misfolded alpha-synuclein proteins that are hallmarks of the disease.
CBHI investigators Cameron McIntyre, Aasef Shaikh, and Camila Kilbane work with the HoloLens.
Martha Sajatovic appointed Rocco L. Motto Professor of Child and Adolescent Psychiatry
A member of our Executive Committee, Dr. Sajatovic received this honor in September, 2019.
which comes as no surprise to her students and trainees....
Thank you for making our second annual Retreat a success!
CBHI's own Cathy Sila M.D. is on the cover, and contributed to the magazine's article on brain health.
National Institute on Aging awards $4.23 million to establish Cleveland Alzheimer’s Disease Research Center
The National Institute on Aging has awarded a $4.23 million grant to CBHI investigators to establish the Cleveland Alzheimer’s Disease Research Center. The two-year award will support the development of a multi-institution collaborative focused on accelerating research for Alzheimer’s disease and related dementias. CBHI's James Leverenz, Lynn Bekris, Alan Lerner, Jonathan Haines, Mark Cohen, Brian Appleby, Martha Sajatovic, and Xiongwei Zhu will lead the effort.
CBHI’s newest study group met for the first time at the CWRU School of Medicine on Thursday, 18 April 2019. The group, originally the AD Study Group, has been re-named in an attempt to generate content useful to all researchers working on neurodegeneration. Join us to discuss funding opportunities and meet other researchers in the field. Not sure how to find us? Check out our Parking page.
T32 award renewed.
CONGRATULATIONS!!! to Xiongwei Zhu Ph.D., Professor of Pathology, and the departments of Pathology, Neurosciences, Physiology & Biophysics, and Genetics & Genome Sciences at CWRU School of Medicine as they have had their T32 grant application, ”Training in Neurodegenerative Diseases,” renewed by the National Institute for Neurological Disorders and Stroke. The grant began with a successful application in 2013 by Joseph LaManna Ph.D. that supported two predoctoral candidates after successful completion of their qualifying exams. This first renewal will support three training slots for a period of five years, trained by approved trainers in each of these departments. A call for applications to fill candidate slots will be forthcoming.
Biomedical Engineers from the Case School of Engineering have described ephaptic coupling between electric fields that can produce a self-propagating wave of electrical activity.
It can reduce the levels of stress hormones in the blood and can mitigate the effects of stress. In a study published by the The Tohoku Journal of Experimental Medicine, researcher JongEun Yim found that "laughter decreases serum levels of cortisol, epinephrine, growth hormone, and 3,4-dihydrophenylacetic acid (a major dopamine catabolite), indicating a reversal of the stress response... "
So, have you laughed today?
Keep up with the latest in stem cell therapy for PD.
Learn more about the ramifications.
Check out our first meeting of the Development Study Group. We had an interactive web platform featured in our Novelty Blitz, and scientific presentations from the Mei lab.
Did you know that diet can profoundly affect brain function?
Learn how a ketogenic diet can reduce seizure frequency in epilepsy.
Have you checked out our cbhi Study Groups?
We have created six Study Groups as areas of focus within CBHI.
- Behavior and Cognition
- Cerebrovascular and Trauma
- Computational Neuroscience, Devices, and Imaging
- Therapeutic Interventions: Drug Development, Stem, and Progenitor Cells
We also have an Investigator Initiated Group on Neuroimmunology.
The Development Study Group will have monthly meetings beginning in November, 2018. Check them out!
Are you interested in starting a group related to Brain Health? Contact us at email@example.com.
Groundbreaking SPRINT Mind study/TEAM
CBHI Investigators from Case Western Reserve University School of Medicine and University Hospitals are major contributors to the SPRINT MIND study, funded by the National Institutes of Health. The study has released preliminary data that seem to indicate that reduction of systolic blood pressure to a target 120 mm Hg (versus 130 mm Hg) may significantly reduce the risk of Mild Cognitive Impairment (MCI), and MCI and dementia (through all causes) combined. Professors at CWRU and UH who participated in the study have also spearheaded the Targeted Management Intervention (TEAM) focused at reducing stroke risk in males of African-American descent. "Our TEAM study has developed an effective behavioral intervention that can help people, especially African-Americans at high risk for stroke, get their blood pressures closer to what we know now are appropriate targets," said Martha Sajatovic MD, Director of the Neurological and Behavioral Outcomes Center at CWRU School of Medicine, and a Professor of Psychiatry at UH, who was first author of the study that appeared in the American Journal of Health Promotion.