2018 Abstracts

Image of two physicians outside of an operating room

Poster Prizes

We will award prizes for the best posters at the CBHI retreat.

ABSTRACTS for the Poster Session at the CBHI Retreat

Study Group Area Abstract
Behavior and Cognition

Behavior

BOARD #1

10:20 AM

Menorah Park Center 4 Brain Health™: A local model for education, engagement and support for community-dwelling adults 

Krystal L. Culler 
Menorah Park Center 4 Brain Health™, Global Brain Health Institute, Youngstown State University

 

Cognitive

BOARD #2

10:30 AM

Upregulation of proteasomal/lysosomal components in the human brains of dementia with Lewy bodies

Qunxing Ding and Haiyan Zhu
Department of Biological Sciences, Kent State University at East Liverpool  

 

Cognitive

BOARD #3

12:20 PM

Intergenerational schools and brain health: from Cleveland and beyond

Peter Whitehouse, Cathy Whitehouse, Brooke King, Danny George

Case Western Reserve University and Intergenerational Schools, Cleveland, OH

Computational Neuroscience, Devices, Imaging

Computational

BOARD #4

12:40 AM

Painting a picture of RNA editing in the brain.

Noel-Marie Plonski1, Madeline Fredrick2, Gabriella Amato2, Caroline Nitirahardjo2, Helen Piontkivska1,2

1School of Biomedical Sciences, 2Department of Biology, Kent State University, Kent OH 44242

 

Electrical Stimulation and Devices

BOARD #5

1:00 PM

Simultaneous development of quantitative tests for context dependent Parkinsonian gait abnormalities and next generation DBS technology

Elizabeth C. Hardin1, Sinem Balta Beylergil2, Cameron McIntyre2, Aasef G. Shaikh 1,3
1Motion Study Lab & Human Performance Virtual Reality Lab, Cleveland FES Center, Cleveland VA Medical Center, 2Dept. of Biomedical Engineering, Case Western Reserve Univ., 3Dept. of Neurology, Cleveland VA Medical Center and Dept. of Neurology, University Hospitals, Cleveland, OH

 

Electrical Stimulation and Devices

BOARD #6

1:10 PM

Sensory function Improvement after 5Hz contralesional rTMS In chronic stroke.

Svetlana Pundik, Jessica McCabe, Margaret Skelly, Curtis Tatsuoka, Heba Akbari, Ela Plow

Case Western Reserve University School of Medicine, Cleveland, OH 44106

 

Electrical Stimulation and Devices

BOARD #7

10:20 AM

Restoring limb function by letting the brain control muscle stimulators directly

 
*Dawn Taylor1,2,3, Frank Willett1,2,3, Tyler Johnson1,2 , Harrison Kalodimos1,2,3
1The Cleveland Clinic, Dept. of Neurosciences, 2Cleveland Functional Electrical Stimulation (FES) Center, Louis Stokes Cleveland VA Medical Center, 3Case Western Reserve University, Dept. of Biomedical Engineering

 

Electrophysiology

BOARD #8

10:30 AM

DGCR2 Important functioning in anxiety within the context of the hippocampus


Heath Robinson, Zhibing Tan, Bin Luo, Wenbing Chen, Lin Mei
Department of Neurosciences, Case Western Reserve University, School of Medicine, Cleveland, OH 44106, USA

 

Imaging

BOARD #9

12:20 PM

Dynamic and adaptive experimentation with real-iime fMRI

SJ Carr1, W Chen2, H Friel3, S Sahoo4, Y Stern5, J Fondran4, S Yang4, D Jordan6, A Crisan6, L Thompson7, HG Taylor8, C Tatsuoka1,4,9
1Neurology, Case Western Reserve University, Cleveland, OH, USA, 2Electrical Engineering and Computer Science, Case Western Reserve University, Cleveland, OH, USA, 3Philips Healthcare, Cleveland, OH USA, 4Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH USA, 5Neurology, Columbia University, New York, NY, USA, 6Radiology, University Hospitals, Cleveland Medical Center, Cleveland OH, USA  Radiology, 7Psychological Sciences, Case Western Reserve University, Cleveland, OH, USA, 8Pediatrics, Case Western Reserve University, Cleveland, OH, USA, 9Neurological Institute, University Hospitals, Cleveland Medical Center, Cleveland OH, USA 

Neurodegeneration

Movement Disorders

BOARD #10

12:40 PM

Important and unimportant patient characteristics for tremor prevalence and tremor irregularity in dystonia

Sinem Balta Beylergil1,2, Laura Scorr3, Adam Cotton3, H. A. Jinnah3,4, and Aasef G. Shaikh2,5

for the Dystonia Coalition Investigators

1Department of Biomedical Engineering, Case Western Reserve University, Cleveland OH, 2Department of Neurology, VA Medical Center, Cleveland OH, 3Department of Neurology, Emory University, Atlanta GA, 30322, 4Department of Human Genetics, Emory University, Atlanta GA, 30322, 5Department of Neurology, Case Western Reserve University, Cleveland OH, and Department of Neurology, University Hospitals, Cleveland OH

 

Movement Disorders

BOARD #11

1:00 PM

Early results on preservation of motor performance in a community-based exercise program 

Elizabeth Stiles, Karen M. Jaffe, David Riley, Benjamin Rossi 
InMotion and John Carroll University, Cleveland, Ohio, USA

 

Myelination

BOARD #12

1:10 PM

miR-27a inhibits maturation of oligodendrocyte precursor cells to mature oligodendrocytes

Ajai Tripathi, Christina Volsko and Ranjan Dutta

Department of Neuroscience, Lerner Research Institute, Cleveland Clinic, Cleveland- 44195

 

Neurodegeneration

BOARD #13

10:20 AM

Vestibular heading perception in Parkinson's Disease patients treated with deep brain stimulation 

Sinem Balta Beylergil1,2, Mark F Walker2,3, Sarah Ozinga1, Angela M Noecker1, Cameron C McIntyre1, and Aasef G. Shaikh2,3,4

for the Dystonia Coalition Investigators

1Department of Biomedical Engineering, Case Western Reserve University, Cleveland OH, 2Department of Neurology,VA Medical Center, Cleveland OH, 3Department of Neurology, Case Western Reserve University, Cleveland OH, 4Department of Neurology, University Hospitals, Cleveland OH

 

Neurodegeneration

BOARD #14

10:30 AM

DJ-1 is critical for the integrity and function of endoplasmic reticulum-mitochondria tethering


Yi Liu*, Sirui Jiang, Xiaopin Ma, Sandra L. Siedlak, Sandy Torres, Shengdi Chen, Xiongwei Zhu 
*Presenting author
Department of Pathology, Case Western Reserve University, Cleveland, Ohio 44106, USA

 

Neurodegeneration

BOARD #15

12:20 PM

Molecular and cellular identification of the immune response in peripheral ganglia following nerve injury


Jon P. Niemi1, Jane A. Lindborg1, Madeline A. Howarth1,2, Kevin W. Liu1, Deepti Mahajan1, Christian Z. Moore1, Richard E. Zigmond1,

1Department of Neurosciences, Case Western Reserve University, Cleveland OH, ,2Hathaway Brown School, Shaker Heights OH.

 

Neurodegeneration

BOARD #16

12:40 PM

A nuclear BHMT-betaine methylation pathway provides neuroprotection in the cuprizone mouse model of multiple sclerosis 

Singhal, N.K.1, Sternbach, S.1, Alkhayer, K.1, Shelestek, J.1, Popescu, D.1, Fleming, S.2, Clements, R.1, Bottiglieri, T.3, Freeman, E.1, McDonough, J.1 
1Department of Biological Sciences and School of Biomedical Sciences, Kent State University, Kent, Ohio 44242. 2Department of Pharmaceutical Sciences, College of Pharmacy, Northeast Ohio Medical University, Rootstown, Ohio, 44272. 3Institute of Metabolic Disease, Baylor Research Institute, Dallas, Texas 75226. E-mail: nsingha1@kent.edu

 

Neurodegeneration

BOARD #17

1:00 PM

Identifying neurodegenerative pathways underlying cortical demyelination in progressive Multiple Sclerosis

Poyi (Bernie) Wu1, Ajai Tripathi2, Christina Volsko2, Ranjan Dutta1,2

1Cleveland Clinic Lerner College of Medicine, 2Department of Neuroscience, Lerner Research Institute, Cleveland Clinic

 

Neurodegeneration

BOARD #18

1:10 PM

Lack of LRP4 in astrocyte enhances beta-amyloid deposition in 5XFAD mice


Hongsheng Zhang, Wenbing Chen, Shu Shu, Zhaoqi Dong, Wanpeng Cui, Kai Zhao, Lei Zhang, Wencheng Xiong, Lin Mei

Department of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, USA; Email:lin.mei@case.edu

 

Prions

BOARD #19

10:20 AM

Teleneurology for research and surveillance of Creutzfeldt-Jakob disease

Brian S Appleby1,2, Kathleen Glisic1, Daniel R Rhoads1,3, Alberto Bizzi4, Mark L Cohen1,3, Supriya Mahajan5
1National Prion Disease Pathology Surveillance Center, Case Western University School of Medicine, 2Departments of Neurology and Psychiatry, Case Western Reserve University and University Hospitals Cleveland Medical Center, 3Department of Pathology, Case Western Reserve University and University Hospitals Cleveland Medical Center, 4Fondazione Instituto Neurologico Carlo Besta IRCCCS, Milan, Italy, 5Neurology Center, Inc., Lorain, Ohio

 

Prions

BOARD #20

10:30 AM

Update on the National Prion Disease Pathology Surveillance Center

Brian S Appleby1,2, Daniel R Rhoads1,3, Aaron Foutz1, Danielle Jordan1, Mark L Cohen1,3
1National Prion Disease Pathology Surveillance Center, Case Western Reserve University 2Departments of Neurology and Psychiatry, Case Western Reserve University and University Hospitals Cleveland Medical Center 3Department of Pathology, Case Western Reserve University and University Hospitals Cleveland Medical Center

Neurodevelopment

Neurodevelopment

BOARD #21

12:20 PM

Distinct regulatory programs control ascending and descending 5-HT axonal architecture

Lauren J. Donovan and Evan S. Deneris

Department of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, OH

 

Neurodevelopment

BOARD #22

12:40 PM

Determining pathogenesis of a rare pediatric intellectual disability and progressive microcephaly syndrome


Katherine Johnson1, Leen Schafer2, Gene Yeo2, Ashleigh Schaffer1

1Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA. 2Department of Cellular and Molecular Medicine, Stem Cell Program and Institute for Genomic Medicine, University of California San Diego, La Jolla, California, USA.

 

Neurodevelopment

BOARD #23

1:00 PM

The open chromatin landscape of 5-HT neurons

W. Clay Spencer and Evan S. Deneris

Department of Neurosciences, Case Western Reserve University, Cleveland, OH USA.

 

Neurodevelopment

BOARD #24

1:10 PM

Molecular mechanisms of phrenic motor neuron development and connectivity

Alicia N. Vagnozzi and Polyxeni Philippidou
Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, OH