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About

A researcher in a white lab coat sits at a computer and reviews scans from her microscope with the microscope in the foreground.

The Department of Physiology and Biophysics at Case Western Reserve University is a leading basic science department with an outstanding international reputation for scientific achievement and teaching excellence.

Innovative Academic Programs

Our PhD, Master of Science and certificate programs provide rigorous training in physiology, biophysics and aerospace physiology. Through interdisciplinary coursework, hands-on research and mentorship from accomplished faculty, students gain the expertise and experience needed to excel in biomedical research, medicine and the health professions.

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Discovery-Driven Mission

We advance scientific discovery, share knowledge with the global scientific community and educate the next generation of researchers, clinicians and innovators. Our work is driven by a commitment to improving human health through research, education and collaboration.

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Research Excellence Across Scales

Our research investigates biological systems at every level—from atoms and molecules to cells, tissues and whole organisms. Faculty expertise spans cardiovascular, renal and nervous system physiology, with a focus on understanding disease mechanisms and developing new therapeutic approaches.

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Advanced Research Resources

Supported by funding from the National Institutes of Health (NIH) and other federal and private sources, our researchers have access to state-of-the-art core facilities for protein expression and purification, molecular biophysics and mouse physiological phenotyping.

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Collaborative Scientific Community

Our department is home to more than 460 faculty members, fellows, students and staff who are united by a shared commitment to collaboration, innovation and scientific inquiry. We foster an environment where diverse perspectives and interdisciplinary partnerships drive discovery.

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Exceptional Location and Opportunities

Located within Case Western Reserve University’s School of Medicine in Cleveland's vibrant University Circle neighborhood, we offer unparalleled access to leading healthcare institutions, research centers, cultural organizations and professional opportunities that enrich the student experience.

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A Legacy of Achievement

Our department has a distinguished history that includes two Nobel Prize recipients and one Lasker Award recipient among its faculty. This legacy continues to inspire groundbreaking research and educational excellence today. 

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