A Home for Collaborative Discovery and Innovation
At Case Western Reserve, we solve pressing problems to improve our world. With the creation of the Interdisciplinary Science and Engineering Building (ISEB), our researchers will be able to take their work even further—collaborating across disciplines to drive change.
A Historic Investment
This $300 million building represents CWRU’s largest-ever project on Case Quad—and an innovative vision for interdisciplinary research.
Making Headlines
From the day it was announced, the ISEB project has made headlines through donor commitments, inspiring ideas and more.
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July 18, 2025The Medical Center Company will begin installing fencing and directional signage on the Case Quad as part of the preparatory work for installing steam and electrical utility services for the Interdisciplinary Science and Engineering Building (ISEB). This work will begin on Monday, July 21, and… -
April 01, 2025As a crane lifted the final structural beam for Case Western Reserve University’s Interdisciplinary Science and Engineering up into the air Friday afternoon, the rain began to pour down. But spirits were not dampened. Cheers erupted as the beam—adorned with signatures of construction crew, staff… -
December 17, 2024When Case Western Reserve University’s Interdisciplinary Science and Engineering Building (ISEB) opens in 2026, it will not only offer collaborative opportunities across the sciences and engineering departments but will also serve as a hub for humanistic inquiry. A $2 million grant from the Jack,…
The innovation that comes out of Case Western Reserve University is going to power our economy in a significant way. The intellectual developments and the inventions are going to translate into commercial advancements that are really important to our future.
The Future of Research, In Numbers
A Place for Hands-on Learning
In the ISEB, research teams will develop groundbreaking solutions to challenges facing our climate, medical system, energy network and beyond—all supported by student researchers who will gain valuable hands-on experience.
Bringing a Vision to Life
Take a look at the architectural renderings of how the ISEB will transform Case Quad.
Exterior Quad Elevation
Exterior Quad Oblique
Exterior MLK Elevation
Exterior Gateway
Interior Grand Atrium Toward MLK
Interior Cafe Toward Stair
Interior Collaborative Space Oblique