Molecular Therapeutics brings together researchers from the College of Arts and Sciences and the School of Medicine to provide adjacencies that accelerate the discovery of new small-molecule therapeutics.
Cluster members work at the intersection of chemistry and biology to validate new therapeutic targets, identify starting points to modulate those targets therapeutically, and refine those starting points toward drug candidates and new intellectual property (IP). While the Cluster will co-localize investigators whose center of gravity lies within this science of therapeutics, the Small Molecule Drug Development Core also facilitates collaborative drug discovery connections across CWRU and across Cleveland.
Problems that Molecular Therapeutics is Working to Solve
Investigators in the Molecular Therapeutics cluster are working toward new therapeutics aimed at:
- Multiple sclerosis
- Genetic diseases causing blindness
- Rare pediatric cancers, including sarcomas
- Autoimmune diseases, including graft-versus-host disease
- More common cancers, including leukemia and lung cancer
Explore Molecular Therapeutics Collaborations
Molecular Therapeutics News
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October 20, 2026This is the final story in a nine-part series introducing the research, people and building that will define Case Western Reserve’s next chapter of discovery. Explore the full series to learn about the seven research clusters and the resources that make the work possible.Editor's note: This story… -
October 09, 2026By assembling researchers with complementary expertise under one roof, Case Western Reserve is building the critical mass needed to move drug discoveries from the laboratory to patients -
September 23, 2026This story is the first in a series introducing the research, people and building that will define Case Western Reserve’s next chapter of discovery. Over the coming weeks, we’ll go inside each of the seven research clusters and the resources that make the work possible.Editor's note: This story was…
Contact Us
To learn more about Molecular Therapeutics, contact cluster faculty lead Drew Adams or meet the team of researchers.