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Robert A. Bonomo, MD
ProfessorDepartment of MedicineSchool of MedicineProfessorDepartment of PharmacologySchool of MedicineProfessorDepartment of Molecular Biology and MicrobiologySchool of MedicineMemberCleveland Center for Membrane & Structural BiologySchool of MedicineEmail: robert.bonomo@med.va.gov
Phone: 216.791.3800
I focus on the molecular mechanisms of antibiotic resistance and structure-function studies of Class A beta-lactamases.
W. Henry Boom, MD
ProfessorDepartment of Molecular Biology and MicrobiologySchool of MedicineChiefDivision of Infectious Diseases & HIV MedicineSchool of MedicineDirectorTuberculosis Research UnitSchool of MedicineEmail: whb@case.edu
Phone: 216.368.1949
My research is in tuberculosis, cytokines, antigen processing, anti-microbial immunity, HIV-1, and pulmonary host defense.
Walter F. Boron, MD, PhD
Distinguished University ProfessorChairmanDepartment of Physiology and BiophysicsEmail: walter.boron@case.edu
Phone: 216.368.8978
My areas of investigation include acid-base homeostasis and gas channels.
Susann M. Brady-Kalnay, PhD
ProfessorDepartment of Molecular Biology and MicrobiologySchool of MedicineProfessorDepartment of NeurosciencesSchool of MedicineProfessorDepartment of PathologySchool of MedicineMemberCancer Imaging ProgramCase Comprehensive Cancer CenterEmail: smb4@case.edu
Phone: 216.368.0330
I research receptor protein tyrosine phosphatases, cell adhesion, and signal transduction, as well as PTPs in adherens junctions and desmosomes.
Heather Broihier, PhD
ProfessorDepartment of NeurosciencesSchool of MedicineDirectorNeurosciences PhD ProgramSchool of MedicineDeputy DirectorMedical Scientist Training ProgramSchool of MedicineEmail: htb@case.edu
Our lab studies synapse assembly and disassembly. We take molecular genetic approaches in Drosophila to define the functions of evolutionarily-conserved signaling pathways in circuit formation and function. We take an integrated approach using conditional genetics, live imaging, high resolution microscopy, electrophysiology, and behavioral assays.
Stacy Brubaker, MSN, MN, RN, CNP
InstructorPhelps Collaborative for Older Adult and Family EngagementFrances Payne Bolton School of NursingEmail: sab159@case.edu
Phone: 216.368.8896
Our lab develops computational approaches for host and microbiome data integration and modeling with the goal of discovering the biological and engineering principles by which cellular systems function. We work in multiple physiological contexts (e.g. gut, joint, reproductive tract) and emphasize computational models of human clinical data together with experimental validation of model results. We are also highly interested in the challenged of translating data from preclinical experimental systems to human physiological contexts through experimental and computational systems biology.
Douglas Brubaker, PhD
Assistant ProfessorDepartment of PathologyCenter for Global Health and DiseasesSchool of MedicineEmail: dkb50@case.edu
The Brubaker Lab develops systems biology approaches to model host-microbiome interactions and identify novel therapeutic strategies for complex inflammatory diseases.
Anna Bruchez, PhD
Assistant ProfessorDepartment of PathologySchool of MedicineEmail: axb1108@case.edu
The Bruchez lab uses unbiased forward genetic screening in human and other mammalian cells to identify novel cellular pathways that affect virus infection. The lab studies emerging viral pathogens, focusing on RNA viruses such as Ebolavirus and Coronaviruses. These high-throughput screening approaches identify novel host-virus interactions that interfere with viral replication, and have uncovered innate immune mechanisms that cells use to resist infection by these viruses. We harness a variety of model viruses, cells, and native SARS-CoV-2 in BSL3 containment, to reveal insights into virus-host interactions and the fundamental cell biology of viral infection.
David Buchner, PhD
Associate ProfessorDepartment of Genetics and Genome SciencesSchool of MedicineEmail: david.buchner@case.edu
Phone: 216.368.1816
Our lab is interested in identifying genes that underlie endocrine disorders ranging from rare monogenic diseases to complex polygenic traits. We also seek to understand the cellular mechanisms underlying these disorders, with a particular focus on insulin signaling and glucose regulation in adipocytes.
Matthias Buck, PhD
ProfessorDepartment of Physiology and BiophysicsSchool of MedicineAssociate ProfessorDepartment of PharmacologySchool of MedicineAssistant ProfessorDepartment of NeurosciencesSchool of MedicineMemberMolecular Oncology ProgramCase Comprehensive Cancer CenterEmail: mxb150@case.edu
Phone: 216.368.8651
I focus in structure/dynamics of protein complexes involved in cancer, neurodegeneration and in cardiovascular development. My research is also in molecular mechanism of plexin, Eph transmembrane receptors and small GTPases in cell motility.