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Drew Adams, PhD
Associate Professor, Department of Genetics and Genome Sciences, School of MedicineMember, Developmental Therapeutics Program, Case Comprehensive Cancer CenterEmail: drew.adams@case.edu
Phone: 216.368.4922
Our lab works at the interface of chemistry and biology to identify new drug targets and lead molecules for the treatment of neurodegenerative and other diseases.
Kumar Alagramam, PhD
Associate Professor, Department of Otolaryngology, School of MedicineProfessor, Department of Genetics and Genome Sciences, School of MedicineEmail: kumar.alagramam@case.edu
Phone: 216.844.7261
My research focuses on genetic basis of hearing loss - Genes involved in sensory hair cell development and noise-induced hearing loss.
Alexandru Almasan, PhD
Professor, Department of Molecular Medicine, School of MedicineAssociate Professor, Department of Environmental Health Sciences, School of MedicineMember, Molecular Oncology Program, Case Comprehensive Cancer CenterEmail: almasaa@ccf.org
Phone: 216.444.9970
My primary research is in the molecular basis of cell death and proliferation control during the genotoxic stress response: BCL-2 family, autophagy regulation, DNA repair, and therapy resistance.
Bela Anand-Apte, MBBS, PhD
Lerner Research InstituteEmail: bela.anand-apte@case.edu
Phone: 216.445.9739
I research molecular mechanisms of abnormal retinal neovascularization and vision loss and development/maintenance of the blood retinal barrier.
Donald D. Anthony, Jr. , MD, PhD
Professor, School of MedicineMember, Immune Oncology Program, Case Comprehensive Cancer CenterEmail: DDA3@case.edu
Phone: 216.368.3540
I focus on immune derangement after long term hepatitis C virus infection that disposes to Hepatocellular Carcinoma. I also study immune and cardiovascular health in Rheumatoid Arthritis, Naive CD4 T cell phenotype and function, senescence, aging and Treg in host response to COVID.
Kristian Baker, PhD
Associate Professor, Department of Genetics and Genome Sciences, School of MedicineMember, Center for RNA Science and Therapeutics, School of MedicineEmail: kristian.baker@case.edu
Phone: 216.368.0277
My lab studies the interplay between translation and mRNA turnover and mRNA quality control. We are particularly interested in understanding the mechanisms underlying nonsense-mediated mRNA decay and how the cell recognizes and rapidly destroys these aberrant transcritps. We are also interested in the identification and function of long noncoding RNAs.
Martín L. Basch, PhD
Assistant Professor, Department of Otolaryngology, School of MedicineAssistant Professor, Department of Genetics and Genome Sciences, School of MedicineEmail: mlb202@case.edu
Phone: 216.844.2323
My primary research is in development and regeneration of the inner ear, including molecular causes of congenital deafness, stria vascularis, and neural crest contributions to the inner ear.
Gürkan Bebek, PhD, MS
Assistant Professor, Department of Nutrition, School of MedicineAssistant Professor, Center for Proteomics and Bioinformatics, School of MedicineAssistant Professor, Computer and Data Sciences Department, Case School of EngineeringEmail: gurkan.bebek@case.edu
Phone: 216.368.4541
My research is primarily in bioinformatic analysis of complex biological networks with novel algorithms, developing personalized/precision medicine paradigm for cancer treatment and systems biology analysis of inflammatory pathways in Alzheimer's Disease.
Saptarshi Biswas
Assistant Professor, Department of Ophthalmology and Visual SciencesEmail: saptarshi.biswas@case.edu
Our immediate goal is to understand the mechanisms of how interactions among neuronal, glial and vascular cells in the central nervous system (CNS) regulate proper CNS angiogenesis and vascular barrier (blood-brain and blood-retinal barriers) maturation during development. Our long-term goal is to identify which of these mechanisms are dysregulated in specific neurological and ocular diseases. We use mouse models, various ex vivo and in vitro assays as well as RNA-sequencing to address these questions.
Robert A. Bonomo, MD
Professor, Department of Medicine, School of MedicineProfessor, Department of Pharmacology, School of MedicineProfessor, Department of Molecular Biology and Microbiology, School of MedicineMember, Cleveland Center for Membrane & Structural Biology, School of MedicineEmail: robert.bonomo@med.va.gov
Phone: 216.791.3800
I focus on the molecular mechanisms of antibiotic resistance and structure-function studies of Class A beta-lactamases.