Trainers Directory

Our lab is interested in the role of the brain barriers (meninges, choroid plexus and blood brain barrier) in the context of neurodevelopmental and neurodegenerative diseases. Particularly, we are interested how the immune cells, vascular cells and stromal cells interact with each other to modulate glial and neuronal function. We use a combination of imaging (macroscopic, confocal, in vivo), flow cytometry (regular and spectral), in vivo intervention (surgeries, pharmacological and genetic) and behavior in mouse models of Autism spectrum disorders and Alzheimer's disease. Our approaches aim at developing new and unconventional therapeutic targets for these disorders.

Antoinen Louveau's Biography 

Our lab explores topics at the interface between molecular virology and the systems-level host response to RNA virus infections, with a special emphasis on RNA driven processes. Incorporating classic virology approaches with innovative sequencing and imaging methods, our approach emphasizes the investigation of host-pathogen interactions in a diverse array of disease-relevant contexts, from COVID-19 to cancer.

Joseph Luna's Biography 

Our lab is generally interested in how resident microbes in the gut interact with the host epithelium to promote homeostasis and how these interactions become altered in pathological states like inflammatory bowel disease. Specifically, we study how small molecules produced by microbes serve as metabolic precursors and receptor ligands, thereby influencing energy balance and gene expression in host cells.

Peder Lund's Biography

I research Eukaryotic gene transcription and RNA polymerase. 

Donal S. Luse's Biography 

My areas of investigation include hematology and pathophysiology of hematologic diseases including bone marrow failure syndromes (BMFS).

Jaroslaw P. Maciejewski's Biography 

I research transcriptional regulation of inflammatory response.

I focus on signal transduction pathways that regulate normal cell growth and are disrupted by oncogenic mutations. In addition, I research molecular mechanisms underlying cancer chemo-preventative agents such as vitamin E.

Danny Manor's Biography

My research is primarily focused on the molecular biology of colon cancer, functional influence of oncogenes and suppressor genes on transformation, metastasis, and response to therapies. 

Sanford Markowitz's Biography 

I perform large-scale mutational experiments characterizing the impacts of protein coding variants on cell function, including infectious diseases and immunity.

Kenneth Matreyek's Biography

My research includes cell death regulation, mechanism of epigenetic aging, the biological significance of DNA methylation age determining the timing of death, and the development of cell death inhibiting small compounds.

Shigemi Matsuyama's Biography