Recent Publications From BETRNet 

1: Blum AE, Ravillah D; BETRNet Consortium, Katabathula RM, Khalighi S, Varadan V, Guda K; BETRNet Contributors, Singh S, Miao Y, Kresak AM, Willis JE, Canto MI, Wang JS, Shaheen NJ, Chak A. HNF4A Defines Molecular Subtypes and Vulnerability to TGFβ-pathway Targeted Therapies in Cancers of the Distal Esophagus. Gastroenterology. 2022 Aug 4:S0016-5085(22)00830-7. doi: 10.1053/j.gastro.2022.07.073. Epub ahead of print. PMID: 35934060.

2: Khalighi S, Joseph P, Babu D, Singh S, LaFramboise T, Guda K, Varadan V.
SYSMut: decoding the functional significance of rare somatic mutations in
cancer. Brief Bioinform. 2022 Jul 18;23(4):bbac280. doi: 10.1093/bib/bbac280.
PMID: 35804437.

3: Sáenz JB, Vargas N, Cho CJ, Mills JC. Regulation of the double-stranded RNA
response through ADAR1 licenses metaplastic reprogramming in gastric epithelium.
JCI Insight. 2022 Feb 8;7(3):e153511. doi: 10.1172/jci.insight.153511. PMID:
35132959; PMCID: PMC8855806.

4: Thota PN, Nasibli J, Kumar P, Sanaka MR, Chak A, Zhang X, Liu X, Uttam S, Liu
Y. Prediction of neoplastic progression in Barrett's esophagus using nanoscale
nuclear architecture mapping: a pilot study. Gastrointest Endosc. 2022
Jun;95(6):1239-1246. doi: 10.1016/j.gie.2022.01.007. Epub 2022 Jan 20. PMID:
35065946; PMCID: PMC9296222.

5: Redston M, Noffsinger A, Kim A, Akarca FG, Rara M, Stapleton D, Nowden L,
Lash R, Bass AJ, Stachler MD. Abnormal TP53 Predicts Risk of Progression in
Patients With Barrett's Esophagus Regardless of a Diagnosis of Dysplasia.
Gastroenterology. 2022 Feb;162(2):468-481. doi: 10.1053/j.gastro.2021.10.038.
Epub 2021 Oct 29. PMID: 34757142; PMCID: PMC9341495.

6: Goldenring JR, Mills JC. Cellular Plasticity, Reprogramming, and
Regeneration: Metaplasia in the Stomach and Beyond. Gastroenterology. 2022
Feb;162(2):415-430. doi: 10.1053/j.gastro.2021.10.036. Epub 2021 Oct 30. PMID:
34728185; PMCID: PMC8792220.

7: Brown JW, Cho CJ, Mills JC. Paligenosis: Cellular Remodeling During Tissue
Repair. Annu Rev Physiol. 2022 Feb 10;84:461-483. doi: 10.1146/annurev-
physiol-061121-035954. Epub 2021 Oct 27. PMID: 34705482; PMCID: PMC8831470.

8: Dong W, Bensken WP, Kim U, Rose J, Berger NA, Koroukian SM. Phenotype
Discovery and Geographic Disparities of Late-Stage Breast Cancer Diagnosis
across U.S. Counties: A Machine Learning Approach. Cancer Epidemiol Biomarkers
Prev. 2022 Jan;31(1):66-76. doi: 10.1158/1055-9965.EPI-21-0838. Epub 2021 Oct
25. PMID: 34697059; PMCID: PMC8755627.

9: Codipilly DC, Krishna Chandar A, Wang KK, Katzka DA, Goldblum JR, Thota PN,
Falk GW, Chak A, Iyer PG. Wide-area transepithelial sampling for dysplasia
detection in Barrett's esophagus: a systematic review and meta-analysis.
Gastrointest Endosc. 2022 Jan;95(1):51-59.e7. doi: 10.1016/j.gie.2021.09.015.
Epub 2021 Sep 17. PMID: 34543648; PMCID: PMC8671247.

10: Radyk MD, Spatz LB, Peña BL, Brown JW, Burclaff J, Cho CJ, Kefalov Y, Shih
CC, Fitzpatrick JA, Mills JC. ATF3 induces RAB7 to govern autodegradation in
paligenosis, a conserved cell plasticity program. EMBO Rep. 2021 Sep
6;22(9):e51806. doi: 10.15252/embr.202051806. Epub 2021 Jul 26. PMID: 34309175;
PMCID: PMC8419698.

11: Cummings LC, Kou TD, Chak A, Schluchter MD, Margevicius S, Cooper GS.
Receipt of Serial Endoscopy Procedures Prior to Esophageal Adenocarcinoma
Diagnosis Is Associated with Better Survival. Dig Dis Sci. 2022
Mar;67(3):1036-1044. doi: 10.1007/s10620-021-06927-1. Epub 2021 Apr 21. PMID:
33881677; PMCID: PMC8528889.

12: Thota PN, Alkhayyat M, Gomez Cifuentes JD, Haider M, Bena J, McMichael J,
Sohal DP, Raja S, Sanaka MR. Clinical Risk Prediction Model for Neoadjuvant
Therapy in Resectable Esophageal Adenocarcinoma. J Clin Gastroenterol. 2022 Feb
1;56(2):125-132. doi: 10.1097/MCG.0000000000001489. PMID: 33405434; PMCID:
PMC8255331.