Interdisciplinary Science and Engineering Building

Illustration of a drug-discovery research lab in the Interdisciplinary Science and Engineering Building, where researchers work at benches and computer desks beneath a giant cell, an atom model, a molecular chain, and a wall-mounted brain connected to circuitry.
October 09, 2026
Collaborative cures: Inside the ISEB’s Molecular Therapeutics research cluster
By assembling researchers with complementary expertise under one roof, Case Western Reserve is building the critical mass needed to move drug discoveries from the laboratory to patients
Illustration of a biomedical research space in the Interdisciplinary Science and Engineering Building, with researchers in lab coats gathered around a heart, a blood vessel, and lungs displayed under glass domes, beneath a giant blood bag, floating blood cells and viruses, and screens showing a brain scan and health data.
October 07, 2026
Targeting solutions: Inside the ISEB’s Precision Diagnostics & Therapeutics research cluster at Case Western Reserve University
How a team of Case Western Reserve researchers is turning a decade of collaboration—and a portfolio of real-world innovations—into the future of precision medicine
Illustration of a materials science lab in the Interdisciplinary Science and Engineering Building with researchers in lab coats working at benches of glassware and microscopes, surrounded by oversized material samples, a robotic arm, a large beaker of bubbling liquid, a roller press, and a testing machine.
October 05, 2026
Forged for impact: Inside the ISEB's Advanced Materials & Manufacturing research cluster
Case Western Reserve researchers are rethinking the materials behind everyday life—and the new Interdisciplinary Science and Engineering Building is giving them the space to do it together.
Illustration depicting a cross-section view of the five-story Interdisciplinary Science and Engineering Building, with illustrated people working in various colorful, science-themed rooms, including laboratories, offices, and gathering areas, surrounded by trees on a campus setting.
September 28, 2026
A new home for discovery and collaboration at Case Western Reserve University
189,000 square feet of dedicated research space.7 research clusters working to solve problems that matter.300 researchers breaking down silos to share expertise, ideas and tools.1 question: What happens when you stop organizing science around disciplines and start organizing it around problems?Case…
An illustration of a space in the Interdisciplinary Science and Engineering building shows researchers, glassware, oversized batteries, tanks, and machinery across orange workstations.
September 28, 2026
Charged with purpose: Inside Case Western Reserve's Galm electrochemical cluster
Researchers in the James M. Galm Electrochemical Engineering & Energy Science research cluster are tackling the chemistry behind batteries, semiconductors, critical metals and clean energy
Illustration depicting a cross-section view of the five-story Interdisciplinary Science and Engineering Building, with illustrated people working in various colorful, science-themed rooms, including laboratories, offices, and gathering areas, surrounded by trees on a campus setting.
September 23, 2026
Where problems are solved: Get to know the new Interdisciplinary Science and Engineering Building at Case Western Reserve University
This story is the first in a series introducing the research, people and building that will define Case Western Reserve’s next chapter of discovery. Over the coming weeks, we’ll go inside each of the seven research clusters and the resources that make the work possible. When the Interdisciplinary…
Rendering of the Kelvin & Eleanor Smith Foundation Terrace
September 09, 2026
The Kelvin & Eleanor Smith Foundation commits $15 million to Interdisciplinary Science and Engineering Building
Gift will support collaborative research and establish The Kelvin & Eleanor Smith Foundation Terrace
James Galm
June 05, 2026
Alumnus James Galm commits $10 million to advance energy and electrochemistry research at Case Western Reserve University
Transformational gift will establish two professorships and a new laboratory in the Interdisciplinary Science and Engineering Building
A modern, multi-story building with glass windows stands in the center. People are walking and sitting on benches in the foreground, surrounded by greenery and trees under a blue sky.
May 13, 2026
Building Blocks: How CWRU’s campus has evolved since 2010
As CWRU celebrates 200 years, its evolving campus tells a story of momentum and impact. Since 2010, 14 new buildings, transformative renovations and new public green spaces have reshaped our landscape.
Abigail Mondragon, Philip Polito and Jack Kellogg at the construction site of the Interdisciplinary Science and Engineering Building. Photography by Nancy Andrews.
April 14, 2026
Inside the build: Meet individuals behind the construction of CWRU’s ISEB project
This October, Case Western Reserve University will open the doors to its new Interdisciplinary Science and Engineering Building (ISEB), a 189,000-square-foot facility designed to foster innovative research across eight collaborative laboratories. While many will have the opportunity to see the…