Faculty
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Faculty

The Biochemistry faculty has a wide range of research interests from cell biology to molecular biophysics. Primary faculty have their main affiliation with the Department of Biochemistry and are based within the department. Secondary faculty have their main affiliation with other departments or centers, including the RNA center. Students can thus work in virtually any field in current biomedical research.

Primary Faculty

Paul Carey Protein-ligand interaction and Raman spectroscopy.
J. Alan Diehl Cell cycle regulation and ubiquitin-dependent protein degradation; integrated stress response and ncRNAs in regulation of the circadian clock and tumorigenesis.
Thomas Gerken Biosynthesis of O-linked glycans.
Hung-Ying Kao Signaling pathways controlled by transcription corepressors and histone deacetylases.
William C. Merrick Mechanism and regulation of eukaryotic protein biosynthesis.
Nelson F. B. Phillips Biochemical mechanisms of tissue-specific transcription factors.
Marianne Pusztai-Carey Structure and function of the insecticidal proteins expressed by the Bacillus thuringiensis family.
David Samols The mammalian response to inflammation; function and regulation of the acute phase reactant, C-reactive protein.
Martin Snider Intracellular movement of cell-surface receptors during endocytosis.
Focco van den Akker Multi-facetted structural approach to understanding the molecular signal transduction events of membrane receptors.
Susan Wang Mechanistic studies of radical S-adenosyl-L-methionine enzymes.
Vivien C. Yee Structure-function studies of enzymes and prion proteins using X-ray crystallography.

Emeriti Faculty

Nikki Harter Molecular mechanisms of adult stem cells and the transformation of melanocytes.
Menachem Shoham Drug discovery against infectious diseases, heart disease and cancer.
Pieter deHaseth Mechanism of RNA polymerase-DNA interactions.

RNA Center Faculty

Jeffery Coller Translational control and mRNA decay.
Jonatha Gott Mechanistic studies of RNA editing in Physarum mitochondria.
Eckhard Jankowsky Molecular Mechanisms of RNA Helicases
Donny Licatalosi Gene expression, alternative RNA regulation, protein-RNA interactions, mammalian germ cell biology.
Jo Ann Wise Mechanism and regulation of pre-mRNA splicing in S. pombe.

Secondary Faculty

Kristian Baker Mechanisms of the nonsense-mediated mRNA decay.
Barbara Bedogni Melanoma development and progression.
Nathan Berger PolyADP-ribose metabolism in DNA repair and replication.
Robert Bonomo β-lactamases and antibiotic resistance.
Henri Brunengraber Nutritional Biochemistry.
Magdalena Grabowska Prostate cancer.
Michael Harris Structure and function of large ribozymes (RNA enzymes) including ribonuclease P RNA. Mechanisms of catalysis by ribozymes
Vincent Hascall Structure, function and metabolism of proteoglycans and hyaluronan in connective tissues.
Faramarz Ismail-Beigi Diabetes, thyroid disease.
Ahmad Khalil Epigenetic Regulation of the Genome, Histone Modifications and Non-coding RNA.
Anton Komar Protein synthesis, protein folding and translational control of gene expression in eukaryotic cells.
Donal Luse Eukaryotic gene transcription and RNA polymerase.
Vincent Monnier Biochemistry of aging.
Krisztina Papp-Wallace β-lactamases and antibiotic resistance.
Jun Qin Biomolecular NMR spectroscopy, signal transduction.
Ganes Sen Mammalian gene expression anantiotensin-converting enzyme and interferon.
Robert Silverman Role of the OAS-RNase L pathway in antiviral innate immunity and cancer.
Marion J. Skalweit Mechanisms of antimicrobial resistance.
Jonathan Stamler Redox-based cellular regulation and signal transduction, and in particular the role of protein S-nitrosylation.
Derek Taylor Structure and molecular mechanisms of macromolecular machines involved in DNA maintenance and RNA maturation and biogenesis.
Saba Valadkhan Role of the mammalian long non-coding RNAs in neurogenesis and cancer.
Michael Weiss Structural mechanisms of human diseases, transcriptional deregulation, and protein misfolding with applications to diabetes and disorders of sexual development.

Other Biochemistry Trainers

Dr. Scott Welford The impact of hypoxia (low oxygen) on tumor initiation and resistance to therapy.

In Memoriam

Richard W. Hanson Hormonal control of gene expression.