The Genomics Core has the privilege of working with many outstanding investigators that cross a wide range of research topics. Listed here are just a few of the projects that the Genomics Core has recently contributed to.
Remember to acknowledge the valuable services provided by the Genomics Core in your research papers and publications:
"This research was supported by the Genomics Core Facility of the CWRU School of Medicine's Genetics and Genome Sciences Department."
Merry CR, Forrest ME, Sabers JN, Beard L, Gao XH, Hatzoglou M, Jackson MW, Wang Z, Markowitz S, Khalil AM (2015)
DNMT1-associated long non-coding RNAs regulate global gene expression and DNA methylation in colon cancer.
Hum Mol Genet.; 24(21):6240-53
Guda K, Veigl ML, Varadan V, Nosrati A, Ravi L, Lutterbaugh J, Beard L, Willson JK, Sedwick WD, Wang ZJ, Molyneaux N, Miron A, Adams MD, Elston RC, Markowitz SD, Willis JE (2015)
Novel recurrently mutated genes in African American colon cancers.
Proc Natl Acad Sci U S A; 112(4):1149-54
Najm FJ, Madhavan M, Zaremba A, Shick E, Karl RT, Factor DC, Miller TE, Nevin ZS, Kantor C, Sargent A, Quick KL, Schlatzer DM, Tang H, Papoian R, Brimacombe KR, Shen M, Boxer MB, Jadhav A, Robinson AP, Podojil JR, Miller SD, Miller RH, Tesar PJ (2015)
Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo.
Merry CR, McMahon S, Thompson CL, Miskimen KL, Harris LN, Khalil AM (2015)
Integrative transcriptome-wide analyses reveal critical HER2-regulated mRNAs and lincRNAs in HER2+ breast cancer.
Breast Cancer Res Treat; 150(2):321-34.
Kevany BM, Zhang N, Jastrzebska B, Palczewski K (2015)
Animals deficient in C2Orf71, an autosomal recessive retinitis pigmentosa-associated locus, develop severe early-onset retinal degeneration.
Hum Mol Genet; 24(9):2627-40
Factor DC, Corradin O, Zentner GE, Saiakhova A, Song L, Chenoweth JG, McKay RD, Crawford GE, Scacheri PC, Tesar PJ (2014)
Epigenomic comparison reveals activation of "seed" enhancers during transition from naive to primed pluripotency.
Cell Stem Cell; 14(6):854-63
Meyers KJ, Mares JA, Igo RP Jr, Truitt B, Liu Z, Millen AE, Klein M, Johnson EJ, Engelman CD, Karki CK, Blodi B, Gehrs K, Tinker L,Wallace R, Robinson J, LeBlanc ES, Sarto G, Bernstein PS, SanGiovanni JP, Iyengar SK (2014)
Genetic evidence for role of carotenoids in age-related macular degeneration in the Carotenoids in Age-Related Eye Disease Study (CAREDS).
Invest Ophthalmol Vis Sci.; 55(1):587-99
Willie B, Hall NB, Stein CM, Jurevic RJ, Weinberg A, Mehlotra RK, Zimmerman PA
Association of Toll-like receptor polymorphisms with HIV status in North Americans.
Genes Immun.; 15(8):569-77