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Robert L. Fairchild, PhD
ProfessorDepartment of Molecular MedicineSchool of MedicineProfessorDepartment of PathologySchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: fairchr@ccf.org
Phone: 216.444.3146
We investigate skin disease, skin and cardiac allograft rejection, and T cell recruitment to inflammation in peripheral tissues.
Christina Farr, PhD
Assistant ProfessorDepartment of PathologySchool of MedicineMemberCenter for Global Health and DiseasesSchool of MedicineMemberPopulation and Cancer Prevention ProgramCase Comprehensive Cancer CenterEmail: cxf288@case.edu
We use a systems immunology approach to investigate host immune-microbe interactions that are important for reproductive health and disease. This combines analysis of clinical specimens, model systems and bioinformatics tools to identify potential interactions.
Seth Field, MD, PhD
ProfessorDepartment of MedicineSchool of MedicineMemberDevelopmental Therapeutics ProgramCase Comprehensive Cancer CenterEmail: seth.field@case.edu
I research cell biology of cancer, fundamental mechanisms of membrane trafficking, discovery of signal transduction pathways that regulate the secretory pathway, and their role in cancer.
James H. Finke, PhD
ProfessorDepartment of Molecular MedicineSchool of MedicineProfessorDepartment of PathologySchool of MedicineMemberMolecular Oncology ProgramCase Comprehensive Cancer CenterEmail: finkej@ccf.org
Phone: 216.444.5186
My research investigates mechanisms by which tumor microenvironment influence the development of T cell immunity to cancer and T cell suppression mechanisms in renal cell carcinoma (RCC).
Paul L. Fox, PhD
ProfessorDepartment of Molecular MedicineSchool of MedicineMemberMolecular Oncology ProgramCase Comprehensive Cancer CenterEmail: foxp@ccf.org
Phone: 216.444.8053
I study the regulation of Endothelial cell motility, the role of Ceruloplasmin in inflammation and Atherosclerosis, and iron homeostasis.
Michael Freeman, PhD
Assistant ProfessorDivision of Infectious Diseases & HIV MedicineCenter for AIDS ResearchSchool of MedicineEmail: mlf62@case.edu
Phone: 216.368.1260
Our lab investigates the mechanisms of immunity and immunopathogenesis during infections, aging, and inflammatory disorders in humans. We use cellular immunology techniques such as flow cytometry of clinical samples and in vitro cultures to better understand how pathogens and chronic inflammation contribute to the activation, expansion, maintenance, and trafficking of T cells and monocytes and how these cells contribute to infection-associated immunopathology and comorbidities in people living with HIV.
David Friel, PhD
Associate ProfessorDepartment of NeurosciencesSchool of MedicineEmail: David.Friel@case.edu
Phone: 216.368.4930
I primarily focus on calcium homeostasis, electrophysiology, ion channels, modulation, optical methods for measuring Ca2+, and modeling.
Wenjian Gan, PhD
Associate ProfessorDepartment of BiochemistrySchool of MedicineMemberMolecular Oncology ProgramCase Comprehensive Cancer CenterEmail: wxg208@case.edu
Phone: 216.368.6122
We are interested in understanding how posttranslational modifications, particularly protein arginine methylation, control diverse cellular processes, and how their dysregulations lead to cancers, and finally to develop small molecule inhibitors targeting these aberrant events for cancer therapy. A range of complementary approaches are used in the lab, including biochemistry, molecular and cellular biology, multi-omics, and mouse models.
Yuan Gao, PhD
Assistant ProfessorDepartment of PharmacologySchool of MedicineMemberCancer Genomics and Epigenomics ProgramCase Comprehensive Cancer CenterEmail: yxg811@case.edu
Phone: 216.368.6632
The primary research objective in our lab is to uncover novel fundamental mechanisms underlying gene expression in cancers. We employ a range of advanced multi-omics technologies to comprehensively detail the oncogenic mechanisms of transcription factors and identify therapeutic targets for treatment.