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Marcin Golczak, PhD
Associate ProfessorDepartment of PharmacologySchool of MedicineMemberCleveland Center for Membrane & Structural BiologyEmail: mxg149@case.edu
Phone: 216.368.0302
I research the physiology of vision at the molecular level and lipid metabolism and homeostasis in the eye. I also design therapeutic strategies against age-related retinal degeneration and dry eye syndrome.
Wendy A. Goodman, PhD
Assistant ProfessorDepartment of PathologySchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: wag@case.edu
Phone: 216.368.3920
We are interested in mechanisms by which endocrine hormones influence the immune response. Receptors for steroid hormones (estrogens, androgens, and progesterone) are broadly expressed and regulate gene transcription in target cells. We study how these pathways operate in immune cells, particularly how they contribute to the balance between immune homeostasis and chronic inflammation & autoimmunity.
Berkley Gryder, PhD
Assistant ProfessorDepartment of Genetics and Genome SciencesSchool of MedicineAssistant ProfessorCase Comprehensive Cancer CenterSchool of MedicineMemberCancer Genomics and Epigenomics ProgramCase Comprehensive Cancer CenterMemberAngie Fowler Adolescent and Young Adult Cancer Research InitiativeEmail: beg33@case.edu
Phone: 216.368.8749
The massively complex human genome is a super-computer that carefully controls its information. It uses chemical-genetic circuits, 3D folding, and signal integration to maintain cell identity and all biological functions. Our lab is excited to unravel the principles of the super-computer we call the epigenome, and do so in the context of cancer.
Neetu Gupta, PhD
Associate ProfessorDepartment of Molecular MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: guptan@ccf.org
Phone: 216.444.7455
I focus on molecular mechanisms regulating antibody-mediated immunity to infections and B cell lymphoma pathogenesis.
Sanjay Gupta, PhD, MS
Carter Kissell Professor and Research DirectorDepartment of UrologySchool of MedicineAssociate ProfessorDepartment of NutritionSchool of MedicineMemberPopulation and Cancer Prevention ProgramCase Comprehensive Cancer CenterEmail: sanjay.gupta@case.edu
Phone: 216.368.6162
I research biomarkers for early detection and prognosis of prostate cancer, molecular targets for prevention and treatment of prostate cancer, and epigenetic mechanisms of gene silencing.
Jonathan Haines, PhD
ChairDepartment of Population and Quantitative Health SciencesSchool of MedicineMary W. Sheldon MD Professor of Genomic SciencesDepartment of Population and Quantitative Health SciencesSchool of MedicineProfessorDepartment of Genetics and Genome SciencesSchool of MedicineProfessorDepartment of Ophthalmology and Visual SciencesSchool of MedicineFounder and DirectorCleveland Institute for Computational BiologySchool of MedicineEmail: jonathan.haines@case.edu
Phone: 216.368.0411
My focus is on genetic epidemiology of neurological and opthalmological disorders, as well as computational methods for biomedical big data.
Philippe Haouzi, MD
ResearcherDepartment of NeurosciencesLerner Research Institute, Cleveland ClinicSchool of Medicine- Regulation of respiration and blood gas homeostasis. In vivo studies in small and large mammals, neural mechanisms of control of respiration
- toxicology: Development of countermeasures against mitochondrial poisons
- Opioid overdose
Clifford V. Harding, MD, PhD
Joseph R. Kahn Professor and Chair of PathologyDepartment of PathologySchool of MedicineInterim Department ChairDepartment of AnatomySchool of MedicineProfessorDepartment of AnatomySchool of MedicineProfessorDepartment of MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterUniversity Hospitals Distinguished PhysicianUniversity Hospitals Cleveland Medical CenterEmail: cvh3@case.edu
Phone: 216.368.3611
My areas of research include immunology, MHC, antigen processing, T cell, phagocytosis, endocytosis, subcellular fractionation, mycobacteria, tumor immunity, tuberculosis, cell biology, exosomes, and extracellular vesicles.
Ann Harris, PhD
Vice Chair of ResearchDepartment of Genetics and Genome SciencesSchool of MedicineProfessorDepartment of Genetics and Genome SciencesSchool of MedicineMemberCancer Genomics and Epigenomics ProgramCase Comprehensive Cancer CenterEmail: ann.harris@case.edu
Phone: 216.368.6651
I research tissue-specific and temporal regulation of gene expression in health and disease. In addition, I study functional genomics of regulatory elements, transcriptional networks, and Chromatin architecture.
Peter J. Harte, PhD
ProfessorDepartment of Genetics and Genome SciencesSchool of MedicineMemberCancer Genomics and Epigenomics ProgramCase Comprehensive Cancer CenterEmail: peter.harte@case.edu
Phone: 216.368.6417
My focus is in transcription activation, repression, Chromatin structure, and homeotic genes.