Search results, if found, will automatically update as terms are selected. If no results are displayed, please revise your search terms.
Filter By:
Stanley L. Hazen, MD, PhD
ChairmanLerner Research InstituteMemberMolecular Oncology ProgramCase Comprehensive Cancer CenterI research the role of gut microbiome in cardiometaboilc diseases and oxidative pathways in inflammation and cardiovascular disease.
Christopher Hine, PhD
Assistant ProfessorDepartment of Molecular MedicineSchool of MedicineMemberMolecular Oncology ProgramCase Comprehensive Cancer CenterEmail: hinec@ccf.org
The research performed in the Hine lab is focused on nutritional, environmental, and genetic factors impacting aging and longevity. To this end, we use in vivo, cellular, and in vitro model systems to understand the hormonal and nutritional regulation of endogenous hydrogen sulfide (H2S) metabolism to cultivate clinically applicable interventions to harness endogenous H2S production for beneficial health outcomes such as increased stress resistance, metabolic fitness, cognition, and lifespan.
Craig Hodges, PhD
Associate ProfessorDepartment of Genetics and Genome SciencesSchool of MedicineAssociate ProfessorDepartment of PediatricsSchool of Dental MedicineDirectorCystic Fibrosis Mouse Models CoreSchool of MedicineEmail: craig.hodges@case.edu
Phone: 216.368.0008
I investigate correction of disease manifestations of Cystic Fibrosis, the creation of mouse models, and modifier genes.
Emina Huang, MD
ProfessorDepartment of SurgerySchool of MedicineEmail: huange2@ccf.org
Phone: 216.442.5097
My lab investigates interactions of intestinal epithelia and the surrounding microenvironment in promoting progression to cancer; colitis-derived tumor initiating cells, induced pluripotent stem cells.
Alex Y.C. Huang, MD, PhD
ProfessorDepartment of PediatricsSchool of MedicineProfessorDepartment of PathologySchool of MedicineCo-LeaderImmune Oncology ProgramCase Comprehensive Cancer CenterDirectorMedical Scientist Training ProgramSchool of MedicineEmail: alex.y.huang@case.edu
Phone: 216.368.1271
I research the regulation between immune activation and tolerance in the pathogenesis of cancer, and intravital 2-photon laser scanning microscopy to study various aspects of in vivo immunity and pathogenesis.
Sudha K. Iyengar, PhD
Professor and Vice Chair for ResearchDepartment of Population and Quantitative Health SciencesSchool of MedicineProfessorDepartment of Genetics and Genome SciencesSchool of MedicineProfessorDepartment of Ophthalmology and Visual SciencesSchool of MedicineFacultyCleveland Institute for Computational BiologySchool of MedicineMemberCancer Genomics and Epigenomics ProgramCase Comprehensive Cancer CenterEmail: sudha.iyengar@case.edu
Phone: 216.368.4388
I research molecular and statistical genetic dissection of multifactorial diseases; common chronic diseases of the eye and the kidney; speech sound disorder.
Mark Jackson, PhD
ProfessorDepartment of PathologySchool of MedicineAssociate Director for Training and EducationCase Comprehensive Cancer CenterDirector, Cancer Biology Training ProgramMemberMolecular Oncology ProgramCase Comprehensive Cancer CenterEmail: mark.w.jackson@case.edu
Phone: 216.368.1276
My area of investigation includes tumor microenvironment, tumor immunology, mestastasis, and cellular transformation.
Beata Jastrzebska, PhD
Associate ProfessorDepartment of PharmacologySchool of MedicineMemberCleveland Center for Membrane & Structural BiologyEmail: bxj27@case.edu
Phone: 216.368.5683
My areas of research include signaling complexes of rhodopsin, rhodopsin oligomeric organization in signal transduction, Molecular bases of light-induced retinal degeneration, and mouse models of retinal degenerative diseases.
Fulai Jin, PhD
Associate ProfessorDepartment of Genetics and Genome SciencesSchool of MedicineAssociate ProfessorDepartment of Computer and Data SciencesCase School of EngineeringCo-LeaderCancer Genomics and Epigenomics ProgramCase Comprehensive Cancer CenterAssociate ProfessorDepartment of Population and Quantitative Health SciencesSchool of MedicineEmail: fulai.jin@case.edu
Phone: 216.368.1811
I study molecular mechanisms and gene regulatory functions of 3D genome architecture, computational and system biology tools for integrative analysis of genomic data, and single cell transcriptome/epigenome technologies in health and disease.
Ge Jin, PhD
MemberPopulation and Cancer Prevention ProgramCase Comprehensive Cancer CenterEmail: ge.jin@case.edu
Phone: 216.368.3791
We are investigating the effect of exosomes, a group of extracellular vesicles (EVs), from virus infected cells on cancer progression, inflammation and co-infection. We are utilizing the "EV-omics", including proteomics, RNAseq, lipidomics and metabolics to identify exosomes cargoes that contribute to diseases. We are also developing exosome therapeutic techniques in cancer treatment and regenerative medicine.