Lin Mei, MD, PhD

Lin Mei Head Shot
Professor and Chair
Department of Neurosciences
School of Medicine
Allen C. Holmes Professor of Neurological Diseases
Department of Neurology


Phone: 216.368.4928

Research Information

Research Interests

The brain contains billions of nerve cells, or neurons, which receive and integrate signals from the environment, and which govern the body's responses. Nervous system activity is made possible by synapses, contacts formed either between neurons or between a neuron and a target cell. Synapses are asymmetric structures in which neurotransmitter molecules are released from the presynaptic membrane and activate receptors on the postsynaptic membrane, thus establishing neuronal communication. As such, synapses are fundamental units of neural circuitry and enable complex behaviors.

Research Projects

Research in our lab has focused on mechanisms of synapse formation, neurotransmission, and synaptic plasticity. Our studies contribute to a better understanding of these processes and development of potential therapeutic strategies for psychiatric disorders such as schizophrenia, autism, and depression and neurological disorders such as muscular dystrophy, spinal cord injury, and epilepsy.‌

External Appointments

Director, Cleveland Brain Health Initiative


Full Publications Can Be Found Here

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