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Qingzhong Kong, PhD
Associate ProfessorDepartment of PathologySchool of MedicineAssociate ProfessorDepartment of NeurologySchool of MedicineAssociate ProfessorDepartment of Environmental Health SciencesSchool of MedicineEmail: qingzhong.kong@case.edu
Phone: 216.368.1756
My lab utilizes mouse models and other approaches to study animal and human prion diseases, especially on zoonosis of animal prions (such as mad cow disease in cattle and chronic wasting disease in deer, elk and moose) and modeling, diagnosis and pathogenesis of various prion diseases. We also are developing gene and cell therapies for neurodegenerative diseases (such as prion diseases and Alzheimer's disease), cancer and diabetes.
Mehmet Koyutürk, PhD
ProfessorDepartment of Computer and Data SciencesCase School of EngineeringMemberCancer Genomics and Epigenomics ProgramCase Comprehensive Cancer CenterEmail: mxk331@case.edu
Phone: 216.368.2963
I analyze high-throughput biological data, algorithmic and analytical methods in systems/network biology, algorithms for data mining and analysis, parallel computing, algorithms for distributed systems, and optimization problems in scientific computing.
Allison Kraus, PhD
Associate ProfessorDepartment of PathologySchool of MedicineEmail: alk127@case.edu
I research self-propagating misfolded proteins of neurodegenerative diseases, including Alzheimer’s, chronic traumatic encephalopathy, Parkinson’s, and prion diseases. I also focus on the analysis of what makes a misfolded protein transmissible, and what makes a transmissible protein seed pathogenic to the host.
Thomas LaFramboise, PhD
ProfessorDepartment of Genetics and Genome SciencesSchool of MedicineMemberCancer Genomics and Epigenomics ProgramCase Comprehensive Cancer CenterEmail: thomas.laframboise@case.edu
Phone: 216.368.0150
We develop and apply computational tools to identify molecular variants that contribute to cancer and related diseases in humans.
Stephanie Langel, PhD
Assistant ProfessorDepartment of PathologySchool of MedicineMemberCenter for Global Health and DiseasesSchool of MedicineEmail: sxl2057@case.edu
Phone: 216.368.0514
The Langel lab is focused on understanding antibody and B cell responses to viral infections, particularly during pregnancy and lactation. To accomplish this, the Langel lab is using single cell technologies, translational animal models, and human clinical samples. The Langel lab's overall goal is to improve maternal and neonatal health around the world.
Justin D. Lathia, PhD
ProfessorDepartment of Molecular MedicineSchool of MedicineCo-LeaderMolecular Oncology ProgramCase Comprehensive Cancer CenterEmail: lathiaj@ccf.org
Phone: 216.445.7475
We use in vivo imaging models to interrogate the tumor microenvironment, examining communication mechanisms in cancer stem cells, currently focused on malignant brain tumors.
John J. Letterio, MD
ProfessorDepartment of PediatricsSchool of MedicineCo-LeaderDevelopmental Therapeutics ProgramCase Comprehensive Cancer CenterEmail: john.letterio@UHhospitals.org
Phone: 216.844.3345
I focus on TGF-ß in immune cell development and function, as well as tumor suppressor functions of TGF-b.
Alan Levine, PhD
ProfessorDepartment of Molecular Biology and MicrobiologySchool of MedicineProfessorDepartment of PharmacologyProfessorDepartment of MedicineSchool of MedicineProfessorDepartment of PathologySchool of MedicineProfessorDepartment of PediatricsSchool of MedicineEmail: alan.levine@case.edu
Phone: 216.368.0342
My research includes intestinal host defense: immune tolerance and immune protection in inflammatory bowel disease, HIV or SARS-CoV-2 infection, and opioid use disorder.
Gina Lewin, PhD
Assistant ProfessorDepartment of PathologySchool of MedicineMemberCenter for Global Health and DiseasesSchool of MedicineEmail: grl48@case.edu
Phone: 216.368.1650
Our human microbiota consists of complex communities where microbial interactions modulate bacterial behavior and influence human health. The Lewin lab is interested in understanding the role of microbial interactions in polymicrobial sites, especially the oral microbiome. We use cutting-edge computational techniques and wet-lab approaches to study these interactions in the context microbial diversity and the dynamic infection environment.
Xiao Li, PhD
Assistant ProfessorDepartment of BiochemistrySchool of MedicineMemberCenter for RNA Science and TherapeuticsSchool of MedicineAssistant ProfessorDepartment of Biomedical EngineeringCase School of EngineeringEmail: xiao.li9@case.edu
Phone: 216-368-0258
I study RNA systems biology in precision medicine.