Frontiers in Pharmacology Journal Club

Fall 2024 Journal Club Schedule

 
Kaylynn Bennett (9/26)

Pharmacological expansion of type 2 alveolar epithelial cells promotes regenerative lower airway repair

Sida Shao¹,², Nan Zhang³, Gregory P. Specht³, Shaochen You³, Lirui Song¹, Qiangwei Fu¹, David Huang¹, Hengyao You³, Jian Shu¹,²,³, Alain Domissy¹, Shuangwei Li¹, Van Nguyen-Tran¹, Sean B. Joseph¹, Arnab K. Chatterjee¹, Jeffrey Jian Chen¹, Peter G. Schultz¹,², and Michael J. Bollong³

Contributed by Peter G. Schultz; received January 3, 2024; accepted March 6, 2024; reviewed by Fred H. Gage and Nathanael S. Gray

 

Dillon Bohinc (10/3)

Sustained B cell depletion by CD19-targeted CAR T cells is a highly effective treatment for murine lupus

Rita Kansal¹, Noah Richardson¹, Indira Neeli¹, Saleem Khawaja¹, Damian Chamberlain¹, Marium Ghani¹, Qurat-ul-ain Ghani¹, Louisa Balazs², Sarka Beranova-Giorgianni³, Francesco Giorgianni³, James N. Kochenderfer⁴, Tony Marion¹, Lorraine M. Albritton¹, and Marko Radic¹

 

William Gregor (10/10)

 5‑HT2ARs Mediate Therapeutic Behavioral Effects of Psychedelic Tryptamines

Lindsay P. Cameron, Seona D. Patel, Maxemiliano V. Vargas, Eden V. Barragan, Hannah N. Saeger, Hunter T. Warren, Winston L. Chow, John A. Gray, and David E. Olson*

 

Elijah Hayes (10/17)

Endocannabinoid release at ventral hippocampal-amygdala synapses regulates stress-induced behavioral adaptation

Veronika Kondev, Mustafa Najeed, Farhana Yasmin, ..., Danny Winder, Brad A. Grueter, Sachin Patel

 
Tristan Lewis (10/31)

Hypoxia Sensing of β-Adrenergic Receptor Is Regulated by Endosomal PI3Kγ

Yu Sun, Kate Stenson, Maradumane L. Mohan, Manveen K. Gupta, Nick Wanner, Kewal Asosingh, Serpil Erzurum, and Sathyamangla V. Naga Prasad

 

Mingda Liu (11/7)

Tumor-agnostic cancer therapy using antibodies targeting oncofetal chondroitin sulfate

Elena Ethel Vidal-Calvo¹,², Anne Martin-Salazar¹, Swati Choudhary¹,², Robert Dagil¹,², Sai Sundar Rajan Raghavan¹, Lara Duvnjak¹,², Mie Anemone Nordmaj¹, Thomas Mandel Clausen², Ann Skafte¹,², Jan Oberkofler¹, Kaituo Wang³, Mette Ø. Agerbæk¹,⁴, Caroline Løppke¹, Amalie Mundt Jørgensen¹,⁴, Daria Ropac¹, Joana Mujollari¹, Shona Willis¹, Agnès Garcias López¹, Rebecca Louise Miller⁵, Richard Torbjörn Gustav Karlsson⁵, Felix Goerdeler⁵, Yen-Hsi Chen⁶, Ana R. Colaço⁷, Yong Wang⁸, Thomas Lavstsen¹, Agnieszka Martowicz⁹, Irina Nelepcu¹⁰,¹¹, Mona Marzban¹⁰,¹¹, Htoo Zarni Oo¹⁰,¹¹, Maj Sofie Ørum-Madsen¹⁰,¹¹, Yuzhuo Wang¹⁰, Morten A. Nielsen¹,², Henrik Clausen⁵, Michael Wierer⁷, Dominik Wolf⁹, Ismail Gögenur¹², Thor G. Theander¹,², Nader Al-Nakouzi²,¹⁰,¹¹, Tobias Gustavsson¹,², Mads Daugaard²,¹⁰,¹¹, and Ali Salanti¹,²

 

Emma Scritchfield (11/14)

A PIKfyve modulator combined with an integrated stress response inhibitor to treat lysosomal storage diseases

William C. Houa, Lynée A. Masseya, Derek Rhoadesa, Yin Wub, Wen Rena, Chiara Franka, Herman S. Overkleeftc, and Jeffrey W. Kellya¹

 

Jaclyn Swigris (11/21)

Dermonecrosis caused by a spitting cobra snakebite results from toxin potentiation and is prevented by the repurposed drug varespladib

Keirah E. Bartlett¹, Steven R. Hall¹,², Sean A. Rasmussen³, Edouard Crittenden¹, Charlotte A. Dawson¹, Laura-Oana Albulescu¹,², William Laprade⁴, Robert A. Harrison¹,², Anthony J. Saviola⁵, Cassandra M. Modahl¹, Timothy P. Jenkins⁶, Mark C. Wilkinson¹, José María Gutiérrez⁷, and Nicholas R. Casewell¹,²