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Jaroslaw P. Maciejewski, MD, PhD
ProfessorDepartment of MedicineSchool of MedicineProfessorDepartment of PathologySchool of MedicineAssociate Director for Translational ResearchCase Comprehensive Cancer CenterMemberCancer Genomics and Epigenomics ProgramCase Comprehensive Cancer CenterEmail: maciejj@ccf.org
Phone: 216.445.5962
My areas of investigation include hematology and pathophysiology of hematologic diseases including bone marrow failure syndromes (BMFS).
Ganapati Mahabaleshwar, PhD
Associate ProfessorDepartment of PathologySchool of MedicineEmail: ghm4@case.edu
Phone: 216.368.5998
I research transcriptional regulation of inflammatory response.
Danny Manor, PhD
ProfessorDepartment of NutritionSchool of MedicineVice ChairDepartment of NutritionSchool of MedicineProfessorDepartment of PharmacologySchool of MedicineMemberMolecular Oncology ProgramCase Comprehensive Cancer CenterEmail: dxm178@case.edu
Phone: 216.368.6230
I focus on signal transduction pathways that regulate normal cell growth and are disrupted by oncogenic mutations. In addition, I research molecular mechanisms underlying cancer chemo-preventative agents such as vitamin E.
Sanford Markowitz, MD, PhD
Ingalls Professor of Cancer GeneticsDepartment of MedicineSchool of MedicineProfessorDepartment of Genetics and Genome SciencesSchool of MedicineProfessorDepartment of Molecular Biology and MicrobiologySchool of MedicinePrincipal InvestigatorCase GI SPORECase Comprehensive Cancer CenterMemberCancer Genomics and Epigenomics ProgramCase Comprehensive Cancer CenterEmail: sxm10@case.edu
Phone: 216-368-1976
My research is primarily focused on the molecular biology of colon cancer, functional influence of oncogenes and suppressor genes on transformation, metastasis, and response to therapies.
Kenneth Matreyek, PhD
Assistant ProfessorDepartment of PathologySchool of MedicineMemberCleveland Center for Membrane & Structural BiologySchool of MedicineEmail: kenneth.matreyek@case.edu
Phone: 216.368.0626
I perform large-scale mutational experiments characterizing the impacts of protein coding variants on cell function, including infectious diseases and immunity.
Ryota Matsuoka, PhD
Assistant ProfessorDepartment of Molecular MedicineLerner Research Institute, Cleveland ClinicCleveland Clinic Lerner College of Medicine of Case Western Reserve UniversityEmail: matsuor@ccf.org
Research projects in the Matsuoka Lab aim to decode genetic programs controlling vascularization, vascular cell diversity, and barrier integrity in the central nervous system. We employ advanced genetic, imaging, and omics approaches to dissect these developmental mechanisms using the zebrafish in vivo model combined with human-derived endothelial cell culture in vitro. Our goal is to discover novel molecular targets from our basic science research and translate this knowledge into developing therapeutics that can repair vascular and neural abnormalities in neurological diseases.
Shigemi Matsuyama, DVM, PhD
Associate ProfessorDepartment of Ophthalmology and Visual SciencesSchool of MedicineAssociate ProfessorDepartment of PathologySchool of MedicineAssociate ProfessorDepartment of PharmacologySchool of MedicineAssociate ProfessorHematology and OncologyDepartment of MedicineAssociate ProfessorDivision of General Medical SciencesAssociate ProfessorCase Western Reserve UniversityAssociate ProfessorCase Comprehensive Cancer CenterAssociate ProfessorDepartment of MedicineSchool of MedicineEmail: sxm193@case.edu
Phone: 216.368.5832
,My research includes cell death regulation, mechanism of epigenetic aging, the biological significance of DNA methylation age determining the timing of death, and the development of cell death inhibiting small compounds.
Primary appointment - Ophthalmology
Other appointments - Pharmacology, Pathology, General Medical Science, Case Comprehensive Cancer Center
Keith R. McCrae, MD
ProfessorDepartment of Molecular MedicineSchool of MedicineProfessorDepartment of PathologySchool of MedicineMemberDevelopmental Therapeutics ProgramCase Comprehensive Cancer CenterEmail: mccraek@ccf.org
Phone: 216.445.8185
My focus is in vascular function in health and disease; inflammation and thrombosis, antiphospholipid antibodies, and miRNA.
Brian McDermott, PhD
Associate ProfessorDepartment of OtolaryngologySchool of MedicineAssociate ProfessorDepartment of Genetics and Genome SciencesSchool of MedicineEmail: brian.m.mcdermott@case.edu
Phone: 216.844.6036
My research involves neurobiology of the auditory hair cell: mechanotransduction, synaptic transmission, and development. I also research Zebrafish models of deafness.
Christopher McFarland, PhD
Assistant ProfessorDepartment of Genetics and Genome SciencesSchool of MedicineAssistant ProfessorCase Comprehensive Cancer CenterSchool of MedicineMemberCancer Genomics and Epigenomics ProgramCase Comprehensive Cancer CenterEmail: christopher.mcfarland@case.edu
Phone: 216.368.3286
My research investigates the roles for passenger mutation in cancer, genetic fitness landscapes, and growth heterogeneity in cancers.
Christopher McFarland's Biography