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Tingwei Mu , PhD
Associate Professor, Department of Physiology and Biophysics, School of MedicineEmail: tingwei.mu@case.edu
Phone: 216.368.0750
My primary research is studying molecular mechanism of ion channel folding, assembly, degradation, trafficking, and function. I also focus on Ion channel folding diseases, such as genetic epilepsy, and proteostasis of membrane proteins.
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Laura Nagy, PhD
Lerner Research Institute, Cleveland Clinic Lerner College of Medicine of Case Western Reserve UniversityEmail: laura.nagy@case.edu
Phone: 216.444.4021
I focus on basic and translational research in the role of innate immunity in alcoholic liver disease; adipose/liver/gut interactions in liver injury.
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Lalitha Nayak, MD
Associate Professor, Department of Medicine, School of MedicineMember, Developmental Therapeutics Program, Case Comprehensive Cancer CenterEmail: lalitha.nayak@case.edu
I research molecular mechanisms linking inflammation and thrombosis.
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Liem Nguyen, PhD
Associate Professor, Department of Molecular Biology and Microbiology, School of MedicineEmail: liem.nguyen@case.edu
Phone: 216.368.3148
I investigate the interactions of pathogenic mycobacteria with host immune systems. Specifically, I research antibiotic resistance, pathogenesis, cell wall assembly and cell division control in Mycobacterium tuberculosis.
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Marvin T. Nieman, PhD, FAHA
Vice Provost and Dean for Graduate StudiesProfessor, Department of Pharmacology, School of MedicineMember, Molecular Oncology Program, Case Comprehensive Cancer CenterEmail: nieman@case.edu
Phone: 216.368.0250
,Nieman provides strategic leadership to support graduate student success in research and teaching, as well as holistic guidance for well-being and career development.
Our lab studies platelet signaling and crosstalk with the immune system in thrombosis and cancer. More specifically, we focus on how proteases initiate intracellular signaling through protease activated receptors. We use structural biology, cell signaling, and animal models to uncover molecular mechanisms then verify these in vivo.
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Nora Nock, PhD, PE
Professor, Department of Population and Quantitative Health Sciences, School of MedicineAssociate Professor, Department of Medicine, School of MedicineMember, Population and Cancer Prevention Program, Case Comprehensive Cancer Center, School of MedicineEmail: nora.nock@case.edu
Phone: 216.368.5653
I research systems biology approaches to interactions of obesity, exercise, and cancer.
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Christine M. O'Connor, PhD
Assistant Professor, Department of Molecular Medicine, School of MedicineMember, Molecular Oncology Program, Case Comprehensive Cancer CenterEmail: oconnoc6@ccf.org
Phone: 216.444.0676
Our lab is interested in understanding how viruses interact with their hosts to cause pathogenesis and disease. Our current work is aimed at elucidating herpesvirus-host interactions, with a particular focus on the human herpesvirus, cytomegalovirus (CMV). We are interested in how CMV usurps cellular processes to maintain long-term latency, drive reactivation given proper cues, and efficiently lytically replicate and spread.
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Rebecca Obeng, MD, PhD
Assistant Professor, Department of Pathology, School of MedicineMember, Immune Oncology Program, Case Comprehensive Cancer CenterEmail: rebecca.obeng@case.edu
Research in my lab is focused on understanding T cell differentiation and function within the tumor microenvironment with an emphasis on (1) the differentiation, in-situ localization, and spatial relationships between subsets of CD8 T cells and other immune markers in the tumor microenvironment; (2) the formation and role of tertiary lymphoid structures in antitumor immunity; (3) strategies to improve PD-1 targeted therapy for patients with cancer; and (4) identification of predictive biomarkers to improve patient selection and prognosis for cancer immunotherapy.
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Pushpa Pandiyan, PhD, MSc
Associate Professor, Biological Sciences, School of Dental MedicineMember, Immune Oncology Program, Case Comprehensive Cancer CenterMember, Center for AIDS ResearchMember, Department of Pathology, School of MedicineMember, Department of Molecular Biology and Microbiology, School of MedicineEmail: pushpa.pandiyan@cwru.edu
Phone: 216.368.2939
My research includes mucosal immunology, immune dysfunction during infections, T-cell subsets and immunoregulation during inflammation and tumorigenesis.
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Nikhil Panicker, PhD
Assistant Professor/Staff, Department of Neurosciences, Lerner Research Institute Cleveland Clinic, School of MedicineEmail: PANICKN@ccf.org
The Panicker lab investigates the molecular mechanisms that drive pathology in Dementia with Lewy bodies (DLB), Parkinson’s Disease (PD), and Alzheimer’s Disease (AD), with the eventual goal of developing therapeutics that block or slow disease progression. We study cell-death pathways in neurodegenerative diseases, and how neuroinflammation (primarily mediated by microglial cells in the brain) contributes to the pathogenesis of neurologic disorders.