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Parameswaran Ramakrishnan, PhD, MS
Associate ProfessorDepartment of PathologySchool of MedicineAssistant ProfessorDepartment of BiochemistrySchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterSchool of MedicineEmail: pxr150@case.edu
Phone: 216.368.2387
I research the regulation of signal transduction in health and disease: autoimmune diabetes, inflammatory diseases and cancer.
Arne Rietsch, PhD
Associate ProfessorDepartment of Molecular Biology and MicrobiologySchool of MedicineAssociate DirectorMedical Scientist Training ProgramSchool of MedicineEmail: arne.rietsch@case.edu
Phone: 216.368.2249
Our lab uses bacterial genetics approaches to study the virulence of the bacterial pathogen Pseudomonas aeruginosa. In particular we focus on the type III secretion system, a molecular syringe that many Gram-negative bacteria use to directly inject proteins into host cells. We are both interested in studying how this exciting nanomachine works, and what the proteins that get injected do.
Andrea Romani , PhD
Associate ProfessorDepartment of Physiology and BiophysicsSchool of MedicineEmail: andrea.romani@case.edu
Phone: 216.368.1625
I study the hormonal regulation of cellular magnesium homeostasis and transport in liver cells under physiological conditions and in pathological diseases including diabetes and alcoholism.
Johnie Rose, MD, PhD
Associate ProfessorCenter for Community Health IntegrationSchool of MedicineDirectorPopulation Cancer Analytics Shared ResourceCase Comprehensive Cancer CenterDirectorClinical Translational Science Doctoral ProgramSchool of MedicineDirectorPreventive Medicine Residency ProgramSchool of MedicineEmail: johnie.rose@case.edu
Phone: 216.368.6860
My work involves applying informatics and simulation modeling techniques to address population health problems, particularly in the area of cancer control/prevention and health disparities.
Kurt W. Runge, PhD
Associate ProfessorDepartment of Genetics and Genome SciencesSchool of MedicineMemberCancer Genomics and Epigenomics ProgramCase Comprehensive Cancer CenterEmail: rungek@ccf.org
Phone: 216.445.9771
My areas of investigation include regulation of the length of telomere repeats and their role in cell physiology, genetic pathways controlling gene silencing and cell aging, and the biology and biochemistry of vitamin K in mammals.
Jiri Safar, MD
ProfessorDepartment of PathologySchool of MedicineProfessorDepartment of NeurologySchool of MedicineMemberCleveland Center for Membrane & Structural BiologySchool of MedicineEmail: jiri.safar@case.edu
Phone: 216.368.4609
My areas of research include protein misfolding, structure-function correlations, amyloid immunochemistry, age-related neurodegeneration, transgenic mice therapeutics, translational medicine, prion diseases, and Alzheimer’s disease.
Helen Salz, PhD
ProfessorDepartment of Genetics and Genome SciencesSchool of MedicineMemberCancer Genomics and Epigenomics ProgramCase Comprehensive Cancer CenterEmail: helen.salz@case.edu
Phone: 216.368.2879
Our lab studies germ cell development. We take advantage of the many genetic, molecular and cell biological tools available in Drosophila to define how sex is determined and maintained in female germ cells, and why errors in this process leads to infertility and germ cell tumors.
Ashleigh Schaffer, PhD
Vice Chair for EducationDepartment of Genetics and Genome SciencesSchool of MedicineAssociate ProfessorDepartment of Genetics and Genome SciencesSchool of MedicineAssociate ProfessorCenter for RNA Science and TherapeuticsSchool of MedicineEmail: ashleigh.schaffer@case.edu
Phone: 216.368.1892
I focus on the genetics of neurodevelopmental disorders and pediatric-onset neurodegeneration, including tissue-specific requirements of ubiquitously expressed proteins in development and disease.
Ashleigh Schaffer's Biography
Jeffrey Schelling, MD
ProfessorDepartment of Physiology and BiophysicsSchool of MedicineEmail: jeffrey.schelling@case.edu
Phone: 216.368.1100
We primarily utilize molecular and advanced imaging techniques in cells and mouse models to imterrogate pathophysiologic mechanisms of diabetes and diabetic kidney disease.
William P. Schiemann, PhD
Vice Dean for Research and InnovationSchool of MedicineGoodman-Blum Professor in Cancer ResearchSchool of MedicineProfessorDepartment of BiochemistrySpecial Advisor to the DirectorCase Comprehensive Cancer CenterDirectorPilot Funding & Scientific InvestmentsCase Comprehensive Cancer CenterMemberMolecular Oncology ProgramCase Comprehensive Cancer CenterEmail: William.Schiemann@case.edu
Phone: 216.368.5763
I focus on molecular mechanisms of breast cancer metastasis, metastatic dormancy, and metastastic relapse.