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William P. Schiemann, PhD
Vice Dean for Research and Innovation, School of MedicineGoodman-Blum Professor in Cancer Research, School of MedicineProfessor, Department of BiochemistryMember, Molecular Oncology Program, Case Comprehensive Cancer CenterEmail: William.Schiemann@case.edu
Phone: 216.368.5763
I focus on molecular mechanisms of breast cancer metastasis, metastatic dormancy, and metastastic relapse.
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William P. Schilling, PhD
Professor, Department of Physiology and Biophysics, School of MedicineVice Chair, Department of Physiology and Biophysics, School of MedicinePhone: 216.778.8965
I research the molecular mechanisms of agonist-induced Ca2+ signaling in mammalian non-excitable cells: TRP family channels.
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Alvin H. Schmaier, MD
Professor, Department of Medicine, School of MedicineProfessor, Department of Pathology, School of MedicineMember, Molecular Oncology Program, Case Comprehensive Cancer CenterEmail: schmaier@case.edu
Phone: 216.368.1172
My primary research is in vascular biology of factor XII, kallikrein/kinin, renin-angiotensin, coagulation and complement systems, cancer and thrombosis, immunology of vascular thrombosis, tyrosine kinase inhibitors and vascular inflammation, ponatinib, malaria, COVID-19 pneumonia, and hereditary angioedema.
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Fredrick R. Schumacher, PhD, MPH
Associate Professor, Department of Population and Quantitative Health Sciences, School of MedicineCo-Leader, Population and Cancer Prevention Program, Case Comprehensive Cancer CenterFaculty, Cleveland Institute for Computational BiologyEmail: frs2@case.edu
Phone: 216.368.0351
My research interests as a genetic epidemiologist focuses on three major areas - deciphering the genomic architecture of complex traits, assessing the shared genomic etiology of complex phenotypes to elucidate the underlying biology, and ascertaining the clinical impact of genomics. My research primarily focuses on cancer by utilizing computational tools.
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Jacob Scott, MD, DPhil
Professor of Radiation Oncology, Department of Molecular Medicine, School of MedicineProfessor of Physics, College of Arts and SciencesCo-Director, Center for AI Enabling Discovery in Disease Biology (AID2B)Associate Director for Data Sciences, Case Comprehensive Cancer CenterMember, Developmental Therapeutics Program, Case Comprehensive Cancer CenterEmail: jgs25@case.edu
Our lab studies cancer and pathogen evolution using theoretical models (mathematical/computational), experimental evolution (in vitro) and data science methods (-omics and AI/ML).
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Ganes C. Sen, PhD
Professor, Department of Molecular Medicine, School of MedicineProfessor, Department of Biochemistry, School of MedicineProfessor, Department of Pathology, School of MedicineMember, Molecular Oncology Program, Case Comprehensive Cancer CenterEmail: seng@ccf.org
Phone: 216.444.0636
I focus on mammalian gene expression of angiotensin-converting enzyme and interferon, in addition to the mechanism of interferon action.
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Anirban Sen Gupta, PhD
Wallace R. Persons Professor, Department of Biomedical EngineeringMember, Cancer Imaging Program, Case Comprehensive Cancer CenterMember, CWRU Center for Imaging ResearchEmail: anirban.sengupta@case.edu
Phone: 216.368.4564
My research includes drug delivery and nanomedicine for treatment of hemostasis, thrombosis, inflammation, immune response and cancer metastasis.
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Carey Shive, PhD
Assistant Professor, Department of Pathology, School of MedicineEmail: carey.shive@case.edu
Phone: 216.368.5238
We study cellular immunology concentrating on chronic viral infections (HIV, HCV, SARS-CoV2) and inflammation in aging. We primarily study human blood cells and plasma to examine the effects of chronic inflammation on health, the mechanisms by which the immune system maintains homeostasis, and how inflammation disrupts the ability of the immune system to reestablish homeostasis after infection and during aging. We have extensive experience in immunological research in the fields of autoimmunity, T cell-specific adaptive immune responses, B-cell antibody responses, cytokines, innate immunity, inflammation, viral infection, and cellular biology. We use cell culture, ELISAs, ELISPOT assays, Cytokine and Antibody Multiplex assays (MSD, Luminex, ELLA), and flow cytometry to test our hypothesizes.
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Scott Sieg
School of MedicineMy areas of investigation include: HIV Immunology, antimicrobial peptides, head and neck cancer tumor microenvironment.
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Robert H. Silverman , PhD
Professor, Department of Molecular Medicine, School of MedicineProfessor, Department of Biochemistry, School of MedicineMember, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer CenterEmail: silverr@ccf.org
Phone: 216.445.9650
My focus is in molecular mechanisms of the antitumor and antiviral activities of interferons.