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William P. Schilling, PhD
ProfessorDepartment of Physiology and BiophysicsSchool of MedicineVice ChairDepartment of Physiology and BiophysicsSchool of MedicinePhone: 216.778.8965
I research the molecular mechanisms of agonist-induced Ca2+ signaling in mammalian non-excitable cells: TRP family channels.
Alvin H. Schmaier, MD
ProfessorDepartment of MedicineSchool of MedicineProfessorDepartment of PathologySchool of MedicineMemberMolecular Oncology ProgramCase Comprehensive Cancer CenterEmail: schmaier@case.edu
Phone: 216.368.1172
My primary research is in vascular biology of factor XII, kallikrein/kinin, renin-angiotensin, coagulation and complement systems, cancer and thrombosis, immunology of vascular thrombosis, tyrosine kinase inhibitors and vascular inflammation, ponatinib, malaria, COVID-19 pneumonia, and hereditary angioedema.
Fredrick R. Schumacher, PhD, MPH
Associate ProfessorDepartment of Population and Quantitative Health SciencesSchool of MedicineCo-LeaderPopulation and Cancer Prevention ProgramCase Comprehensive Cancer CenterFacultyCleveland Institute for Computational BiologyEmail: frs2@case.edu
Phone: 216.368.0351
My research interests as a genetic epidemiologist focuses on three major areas - deciphering the genomic architecture of complex traits, assessing the shared genomic etiology of complex phenotypes to elucidate the underlying biology, and ascertaining the clinical impact of genomics. My research primarily focuses on cancer by utilizing computational tools.
Jacob Scott (he/him), MD, DPhil
Associate ProfessorDepartment of Molecular MedicineSchool of MedicineAdjunct Associate ProfessorDepartment of PhysicsSchool of MedicineAssociate Director for Data SciencesCase Comprehensive Cancer CenterMemberDevelopmental Therapeutics ProgramCase Comprehensive Cancer CenterEmail: jgs25@case.edu
Our lab studies cancer and pathogen evolution using theoretical models (mathematical/computational), experimental evolution (in vitro) and data science methods (-omics and AI/ML).
Ganes C. Sen, PhD
ProfessorDepartment of Molecular MedicineSchool of MedicineProfessorDepartment of BiochemistrySchool of MedicineProfessorDepartment of PathologySchool of MedicineMemberMolecular Oncology ProgramCase Comprehensive Cancer CenterEmail: seng@ccf.org
Phone: 216.444.0636
I focus on mammalian gene expression of angiotensin-converting enzyme and interferon, in addition to the mechanism of interferon action.
Anirban Sen Gupta, PhD
ProfessorDepartment of Biomedical EngineeringCase School of EngineeringSchool of MedicineMemberCancer Imaging ProgramCase Comprehensive Cancer CenterEmail: anirban.sengupta@case.edu
Phone: 216.368.4564
My research includes drug delivery and nanomedicine for treatment of hemostasis, thrombosis, inflammation, immune response and cancer metastasis.
Carey Shive, PhD
Assistant ProfessorDepartment of PathologySchool of MedicineEmail: carey.shive@case.edu
Phone: 216.368.5238
We study cellular immunology concentrating on chronic viral infections (HIV, HCV, SARS-CoV2) and inflammation in aging. We primarily study human blood cells and plasma to examine the effects of chronic inflammation on health, the mechanisms by which the immune system maintains homeostasis, and how inflammation disrupts the ability of the immune system to reestablish homeostasis after infection and during aging. We have extensive experience in immunological research in the fields of autoimmunity, T cell-specific adaptive immune responses, B-cell antibody responses, cytokines, innate immunity, inflammation, viral infection, and cellular biology. We use cell culture, ELISAs, ELISPOT assays, Cytokine and Antibody Multiplex assays (MSD, Luminex, ELLA), and flow cytometry to test our hypothesizes.
Scott Sieg
School of MedicineMy areas of investigation include: HIV Immunology, antimicrobial peptides, head and neck cancer tumor microenvironment.
Jerry Silver, PhD
ProfessorDepartment of NeurosciencesSchool of MedicineEmail: jxs10@case.edu
Phone: 216.368.2150
I research the role of glial cells in development and regeneration of neural circuits, nerve regeneration, glia, and axon guidance.
Robert H. Silverman , PhD
ProfessorDepartment of Molecular MedicineSchool of MedicineProfessorDepartment of BiochemistrySchool of MedicineMemberCancer Genomics and Epigenomics ProgramCase Comprehensive Cancer CenterEmail: silverr@ccf.org
Phone: 216.445.9650
My focus is in molecular mechanisms of the antitumor and antiviral activities of interferons.