Small Molecule Analysis

Current Small Molecule Quantification Assays Offered

  • Cocaine and Metabolites
  • GSH/GSSG
  • Nucleotides
  • Lysophosphatidic acids (LPAs)
  • Leukotrienes
  • TCA metabolites
  • Tryptophan/kynurenine
  • Choline/Acetycholine

 

In addition to providing the above analytical assays the core can provide custom method development for drugs and or metabolites per request. In addition to providing customized panels, starting in 2019 the core will offer the Biocrates 400 plus metabolite panel for cells and biological matrices.

 

The Core using the following mass spectrometery instrumentation for these assays:

 

 

Contacts

 

Targeted Drug and Drug Metabolites – Xiaolin Li

Endogeneous Metabolites – Saussan Azzam

 

 

Related Articles

A Targeted Mass Spectrometry Assay for Detection of HIV Gag Protein Following Induction of Latent Viral Reservoirs.

Schlatzer D, Haqqani AA, Li X, Dobrowolski C, Chance MR, Tilton JC.

Anal Chem. 2017 May 16;89(10):5325-5332. doi: 10.1021/acs.analchem.6b05070. Epub 2017 May 3.