The research performed in the Hine lab is focused on nutritional, environmental, and genetic factors impacting aging and longevity. To this end, we use in vivo, cellular, and in vitro model systems to understand the hormonal and nutritional regulation of endogenous hydrogen sulfide (H2S) metabolism to cultivate clinically applicable interventions to harness endogenous H2S production for beneficial health outcomes such as increased stress resistance, metabolic fitness, cognition, and lifespan.
Department of Molecular Medicine
School of Medicine
Molecular Oncology Program
Case Comprehensive Cancer Center