Chao-Pin Hsiao, PhD, RN

Assistant Professor
Frances Payne Bolton School of Nursing
Member
Cancer Prevention
Control & Population Research Program
Case Comprehensive Cancer Center

Teaching Information

Teaching Interests

  • Translational Research
  • Symptom Management
  • Oncology Nursing

Research Information

Research Interests

  • Cancer patient symptom management
  • Molecular-genetic mechanisms of cancer-related fatigue
  • Mitochondrial bioenergetic mechanisms of radiation-induced fatigue

Research Projects

Ongoing

Mitochondrial Bioenergetic Mechanism of Cancer Related Fatigue

Principal Investigator: Chao-Pin Hsiao, PhD, RN

Funding Agency: NIH, National Institute of Nursing Research (K01)

Period: 08/2015-05/2018

  • This study examine the association among certain genes, mitochondrial bioenergetics, and fatigue in prostate cancer patients receiving localized radiation therapy over a period of time and to compare differences in gene expression, the mitochondrial bioenergetics profile, and fatigue between the patients with radiation therapy and without radiation therapy (on active surveillance).

Mitochondrial Bioenergetic Mechanism and  Cancer Related Fatigue in prostate Cancer: Bridge the Essential Knowledge and Skills of Mitochondrial Bioenergetics

Principal Investigator: Chao-Pin Hsiao, PhD, RN

Funding Agency: ACES+ ADVANCE Opportunity Grant, Case Western Reserve University

Period: 03/2016-03/2017

  • This grant supports travel to another facility to obtain essential and advanced training program in mitochondrial metabolism and bioenergetics, developing successful competitive research proposals integrating bench science, clinical practice, and novel interventions, stemming from a molecular-genetics perspective of symptom management in cancer.

Completed

Changes in Mitochondrial Bioenergetics and Cancer-Related Fatigue in Prostate Cancer

Principal Investigator: Chao-Pin Hsiao, PhD, RN

Funding Agency: Oncology Nursing Society Foundation (RE01)

Period: 01/2014-01/2016

  • This is a pilot study exploring mitochondrial functions and fatigue experience in patients receiving localized radiation therapy. It focuses on establishing laboratory procedures and baseline data.

Relationship between Mitochondrial Dysfunction and Fatigue in Cancer Patients Following External Beam Radiation Therapy

Principal Investigator: Chao-Pin Hsiao, PhD, RN

Funding Agency: NIH, National Institute of Nursing Research, Intramural Research Program

Period: 05/2009-01/2014

  • (10-NR-0088) This study explored changes in the expression of mitochondrial genes that are associated with fatigue symptoms of prostate cancer patients receiving localized radiation therapy.

Investigating Molecular-Genetic Correlates of Fatigue in Cancer Patients Receiving Localized External Beam Radiation Therapy

Role: Lead Associate Investigator                 

Principal Investigator: L. Saligan, PhD, RN, FAAN

Funding Agency: NIH, National Institute of Nursing Research, Intramural Research Program

Period: 05/2010-01/2014

  • (10-NR-0088) This study explored explores the molecular-genetic mechanisms underlying fatigue and the cluster of symptoms (urinary, sexual, gastrointestinal, and psychiatric) experienced by prostate cancer patients undergoing External Beam Radiation Therapy (EBRT).

Investigating Correlates of Fatigue in Cancer Patients Receiving Treatment

Principal Investigator: Chao-Pin Hsiao, PhD, RN

Funding Agency: NIH, National Institute of Nursing Research, Intramural Research Program

Period: 06/2011-01/2014

  • (10-NR-0014) This study explored explores the molecular-genetic mechanisms underlying fatigue experienced by cancer patients receiving various therapies (e.g. immune therapy, hormone therapy, and chemotherapy).

Awards and Honors

The Junior Research Researcher Award
Midwest Nursing Research Society

Professional Memberships

Member, Midwest Nursing Research Society (MNRS), 2013-present
Member, Oncology Nursing Society, 2003 – present
Member, Sigma Theta Tau, Beta Mu Chapter 2003 – present
Member, International Sigma Theta Tau, 1999 – present

Publications

Education

Doctor of Philosophy
Injury Mechanisms and Biobehavior
University of Arizona, School of Nursing
Master of Science in Nursing
Oncology
National Taiwan University, School of Nursing
Bachelor of Science in Nursing
National Taiwan University, School of Nursing

Residencies, Internships and Fellowships

Postdoctoral
National Institutes of Health, National Institute of Nursing Research, Symptom Biology Unit, Bethesda, Md.