Tissue Procurement
- Tissue Procurement team works directly with surgical pathologists to obtain samples
- Custom protocol development for tissue collection and processing
- Quality control reviews on human tissue samples are conducted to verify diagnosis before release to investigators (unless needed immediately)
- Normal, benign, diseased, and malignant tissues from surgeries and autopsies
- Matched normal adjacent tissue and tissues from different organ sites of the same donor with special emphasis on accessing metastatic samples
- Tissues are collected from over 50 anatomic sites
- No samples are collected from individuals with known infectious illnesses
- Fetal biospecimens are not collected due to state and local statutes
- Patient confidentiality is strictly maintained through the use of sample code numbers
- Coded Surgical Pathology or Autopsy Reports containing final diagnosis
- Tissue type and histopathologic status, sample weight or dimensions
- Demographics (age in years, race, gender)
- Chart reviews performed upon request to obtain additional clinical information
- De-linked specimens are not traceable, and as such no further information can be obtained for these samples.
| Service | Unit | Fee |
|---|---|---|
| Tissue - prospectively procured initial sample (includes QC) | per sample | $49.50 |
| Banked Samples(Frozen and FFPE) | per sample | $57.75 |
| Blood (Discarded) | per sample | $6.60 |
| Serum (Discarded) | per sample | $13.20 |
| Basic Chart reviews | per case | $49.50 |
| Detailed Chart review | per hour | $60 |
| Sample long-term storage (>1 months) | per vial | $7.15 |
| Shipping/Handling (with Prepaid FedEx or UPS account) | per vial | $22 |
| *Specialized services are available |
Histology
- Fixation of researcher-supplied tissues
- Paraffin or OCT embedding
- Serial sectioning and custom orientations
- Unstained slides, Hematoxylin and Eosin (H&E) staining, special morphological stains, and enzyme histochemistry available
| Service | Unit | Fee |
|---|---|---|
| Block, paraffin or OCT (Tissues dissected to size and fixed by researcher) | per block | $9 |
| Slides, unstained | per slide | $6 |
| RNase free handling charge for cryostat cutting (in addition to sample charge) | per OCT block | $16.50 |
| RNase free handling charge for paraffin cutting (in addition to sample charge) | per paraffin block | $33 |
| Staining charge for H&E or other simple stains including Cresyl Violet, Methyl Green, Methylene Blue, etc. | per slide | $3 |
| Staining charge for complex stains including Copper, Elastin, Trichromes, Oil Red O, PAS,etc. | per slide | $9 |
| Slide box if not provided by researcher (prices shown for 10, 25, or 100 place boxes) | per box | $2.50* $5* $10* |
| Rental of microtome or cryostat | 30 minutes | $19.25 |
| Agar/Paraffin embedding of cell pellets | per block | Tech time + $9 |
*Rush orders can be performed for an additional 50% fee.
**Slide box price may vary depending on market price
Immunohistochemistry (IHC) and Immunofluorescence and In situ hybridization
- Routine immunohistochemistry and protocol development of commercially available and novel antibodies
- Over 100 IHC assays available
- 12 singleplex and multiplex RNA in situ hybridization assays optimized (please inquire)
| Service | Unit | Fee |
|---|---|---|
| IHC (Investigator-supplied antibody) | per slide | $41 |
| IHC (Core-supplied antibody) | per slide | $47 |
| IHC Double stain | per slide | $52 |
| IHC Triple stain | per slide | $57 |
| IHC Assay Development (Investigator-supplied antibody) | panel of 4 runs | $550 |
| TUNEL in situ assay | per slide | $60.50 |
| In-situ hybridization | per slide | $77 |
| IHC/ISH dual method stain | per slide | $94 |
Microscopy and Digital Imaging
- Light, fluorescence, and phase contrast microscopy
- Digital imaging for Histology, IHC, & TMA prepared slides
| Service | Unit | Fee |
|---|---|---|
| Consultation, set-up, and first slide photomicrograph | per job | $33 |
| Additional slides | per photo | $4.50 |
| Hardcopy photos (color laserjet printer, 8.5" x 11", std. paper) | per photo | $2.50 |
*Light, phase contrast, fluorescence (DAPI, FITC, and TRITC). Service offered to histology, IHC and TMA facility users.
Tissue Microarrays (TMAs)
- Custom design and production of Tissue Microarrays
| Service | Unit | Fee |
|---|---|---|
| TMA Arrayer Set Up/Programming | per TMA | $275 |
| TMA unstained slide (TMA from researcher) | per slide | $20 |
| TMA unstained slide (TMA from core facility) | per slide | $200 |
| Design TMA, CoPath search for potential TMA source blocks, obtaining blocks, scribing areas, etc. | Negotiate with collaborating pathologist | |
| Core punch | per core | $7 |
| Duplicate Punch | per duplicate core | $3.50 |
| QC pathologist review | per core | $1 |