Fabin Dang earned a PhD in Biochemistry and Molecular Biology from the University of Chinese Academy of Sciences in 2017. He subsequently completed postdoctoral training at Beth Israel Deaconess Medical Center, Harvard Medical School, from September 2017 to May 2021. From June 2021 to May 2024, he served as an Instructor in the Department of Pathology at Beth Israel Deaconess Medical Center, Harvard Medical School. In June 2024, Dr. Dang joined the Department of Genetics and the Case Comprehensive Cancer Center as an Assistant Professor.
Research Information
Research Projects
The immune system is a robust and essential system that distinguishes self from non-self, recognizes and eliminates pathogenic signals, and maintains homeostasis. A robust and healthy immune response relies on energy, which is provided by metabolism. Hence, the metabolic status of cancer and immune cells plays crucial roles in regulating antitumor immunity. Our laboratory is primarily focusing on understanding the intricate crosstalk between cancer metabolism and antitumor immunity. Specifically, we are curious about how the metabolic status of cancer and immune cells influences antitumor immunity by driving changes in protein post-translational modifications. Additionally, we are interested in investigating the intracellular trafficking of membrane proteins and their novel functions within cells beyond serving as membrane receptors. Moreover, we are intrigued by exploring the involvement of epigenetic regulation in tumorigenesis, along with their potential as anticancer targets. The ultimate goal of our research is to offer novel targeted therapeutic strategies for clinical translation to combat cancer.