(INFO GRAPHIC OF FACTS HERE)
Case Comprehensive Cancer Center (Case CCC) is one of just 57 National Cancer Institute (NCI)-designated comprehensive cancer centers in the United States and the only NCI-designated consortium comprehensive cancer center in Ohio.
An NCI designation is the nation's highest recognition for cancer centers conducting research. It recognizes institutions that demonstrate scientific excellence, leadership, and the ability to translate discoveries into meaningful advances in cancer prevention, detection, diagnosis, treatment, survivorship, and community health.
To earn and maintain Comprehensive Cancer Center designation, a center must demonstrate exceptional strength across the full spectrum of cancer research—including basic (laboratory), clinical, and population sciences—while integrating education and training, community outreach and engagement, and shared scientific resources that accelerate discovery and improve health.
Why a Consortium Comprehensive Cancer Matters
The process of becoming a cancer center as defined by the National Institutes of Health/National Cancer Institute (NIH/NCI) involves applying for a highly competitive cancer center support grant every 5-7 years through a rigorous process mandated by the NIH/NCI. If awarded, the Center holds the grant and its director becomes the grant’s principal investigator, responsible for outcomes-based stewardship of this funding.
After its founding in 1987, Case CCC was designated an NCI-comprehensive cancer center in 1998 and, in 2004, became a consortium comprehensive cancer center charged with integrating joint cancer research and care programs, clinical trials, collaborative community outreach, and shared training grants, to execute a shared cancer research agenda among Case Western Reserve University, University Hospitals, and Cleveland Clinic.
For patients and communities in the 15 Northeast Ohio counties in Case CCC’s service area, this consortium model provides access to the combined expertise, scientific discoveries, and clinical resources of three nationally recognized institutions rather than a single cancer center.
By uniting more than 400 cancer researchers and clinicians, the consortium accelerates the translation of laboratory discoveries into new prevention strategies, earlier detection methods, innovative clinical trials, and more personalized treatments. It also enables coordinated community outreach to reduce cancer disparities, expand access to screening and education, and ensure that people throughout Northeast Ohio benefit from the latest advances in cancer research and care, regardless of where they receive treatment.
Our NCI Journey
1987 — NCI Cancer Center Designation
Case Comprehensive Cancer Center is established through a partnership between Case Western Reserve University and University Hospitals and receives its first National Cancer Institute Cancer Center designation.
1998 — Comprehensive Cancer Center Designation
After demonstrating excellence across laboratory, clinical, and population science, along with education and community outreach, Case CCC earns NCI Comprehensive Cancer Center designation.
2004 — Consortium Expansion
Cleveland Clinic joins Case Western Reserve University and University Hospitals, expanding Case CCC into an NCI-designated consortium comprehensive cancer center and creating one of the nation's most distinctive collaborative cancer research environments.
1987–Present — Continuous NCI Support
For nearly four decades, Case CCC has successfully competed for continuous National Cancer Institute Cancer Center Support Grant funding, reflecting sustained excellence in scientific leadership, research infrastructure, and collaborative innovation.
For Researchers
Acknowledging Case CCC Support
Investigators who receive support through Case CCC Shared Resources, pilot funding, scientific programs, or other Cancer Center-supported initiatives are required to acknowledge that support in publications, abstracts, presentations, press releases, and other scholarly communications using the following statement:
"This project was supported by the Case Comprehensive Cancer Center, which is funded by the National Cancer Institute of the National Institutes of Health, P30CA043703. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH."
NIH Public Access Policy
Publications acknowledging support from Case CCC must be submitted to PubMed Central in accordance with the NIH Public Access Policy. Investigators should refer to current NIH guidance for submission requirements and compliance procedures.
Case CCC shared resource users, pilot grant awardees, and researchers supported by Case CCC programs are required to acknowledge Case CCC support with the following text in each abstract, press release, or other publication:
“This project was supported by the Case Comprehensive Cancer Center, which is funded by the National Cancer Institute of the National Institutes of Health, P30CA043703. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.”
When support from Case CCC is acknowledged in a publication, the publication must be submitted to PubMed Central to comply with the NIH Public Access Policy. Refer to these sites for submission requirements.