Tables of Cases Examined

 
National Prion Disease Pathology Surveillance Center Cases Examined¹

Updated July 8th, 2020

Year Total Referrals² Prion Disease Sporadic Familial Iatrogenic vCJD
1999 & earlier 381 230 200 27 3 0
2000 145 102 90 12 0 0
2001 209 118 110 8 0 0
2002 241 144 124 18 2 0
2003 259 160 137 21 2 0
2004 316 181 164 16 0 1³
2005 327 178 156 21 1 0
2006 365 179 159 17 1 2
2007 374 210 191 19 0 0
2008 384 221 205 16 0 0
2009 397 231 210 20 1 0
2010 401 246 218 28 0 0
2011 392 238 214 24 0 0
2012 413 244 221 23 0 0
2013 416 258 223 34 1 0
2014 355 208 185 21 1 1
2015 401 263 243 20 0 0
2016 396 277 248 29 0 0
2017 375 266 247 19 0 0
2018 309 223 204 18 1 0
2019 418 270 247 21 0 0
2020 189 90 65 6 1 0
TOTAL 74636 45377 40658 4389 14 4

1Listed based on the year of death or, if not available, on the year of referral; 2Cases with suspected prion disease for which brain tissue was submitted; 3Disease acquired in the United Kingdom; 4Disease acquired in the United Kingdom in one case and in Saudi Arabia in the other; 5Disease possibly acquired in a Middle Eastern or Eastern European country; 6Includes 32 cases in which the diagnosis is pending, and 19 inconclusive cases; 7Includes 20 (2 from 2019, 18 from 2020) cases with type determination pending in which the diagnosis of vCJD has been excluded. 8The sporadic cases include 3956 cases of sporadic Creutzfeldt-Jakob disease (sCJD), 70 cases of Variably Protease-Sensitive Prionopathy (VPSPr) and 35 cases of sporadic Fatal Insomnia (sFI). 9Total does not include 275 Familial cases diagnosed by blood test only.