NPDPSC Table of Cases Examined

 

Updated quarterly.
Last updated on: August 26th, 2024

Year¹ Total Neuropath Referrals² Prion Disease Sporadic Genetic Iatrogenic vCJD
1999 & earlier 384 232 202 27 3 0
2000 145 102 90 12 0 0
2001 209 118 110 8 0 0
2002 241 144 124 18 2 0
2003 259 160 137 21 2 0
2004 315 180 163 16 0 1³
2005 330 179 157 21 1 0
2006 365 179 159 17 1 2
2007 374 210 191 19 0 0
2008 384 221 205 16 0 0
2009 397 231 210 20 1 0
2010 402 247 219 28 0 0
2011 392 238 214 24 0 0
2012 413 244 221 23 0 0
2013 416 258 223 34 1 0
2014 355 208 185 21 1 1
2015 401 262 243 19 0 0
2016 396 278 247 30 0 0
2017 376 266 247 19 0 0
2018 311 221 202 18 1 0
2019 437 281 259 22 0 0
2020 367 253 228 24 1 0
2021 345 248 226 22 0 0
2022 341 229 208 21 0 0
2023 324 237 217 17 1 0
2024 225 141 100 2 0 0
TOTAL 89056 55677 49878 5199 15 4

 

1Listed based on the year of death or, if not available, on the year of referral; 
2Cases with suspected prion disease for which brain tissue and/or blood (in familial cases) were submitted. Includes 44 autopsy coordinated cases pending tissue receipt; 
3Disease acquired in the United Kingdom; 
4Disease acquired in the United Kingdom in one case and Saudi Arabia in the other; 
5Disease possibly acquired in a Middle Eastern or Eastern European country; 
6Includes 26 cases in which the diagnosis is pending (from 1961, and 25 from 2024), and 20 inconclusive cases; 
7Includes 42 (1 from 2016, from 2023, and 39 from 2024) cases with type determination pending in which the diagnosis of vCJD has been excluded. 
8The sporadic cases include 4,855 cases of sporadic Creutzfeldt-Jakob disease (sCJD), 92 cases of Variably Protease-Sensitive Prionopathy (VPSPr), and 40 cases of sporadic Fatal Insomnia (sFI). 
9Total does not include 324 Familial cases diagnosed by blood test only.

 


For a downloadable PDF version of our quarterly table, please click the link below: 

NPDPSC Table of Cases Examined