Tables of Cases Examined

Updated August 14, 2019

Year Total Referrals² Prion Disease Sporadic Familial Iatrogenic vCJD
1999 & earlier 380 230 200 27 3 0
2000 145 102 90 12 0 0
2001 209 118 110 8 0 0
2002 241 144 124 18 2 0
2003 259 160 137 21 2 0
2004 316 181 164 16 0
2005 327 178 156 21 1 0
2006 365 179 159 17 1 2⁴
2007 374 210 191 19 0 0
2008 384 221 205 16 0 0
2009 398 232 210 21 1 0
2010 401 246 218 28 0 0
2011 392 238 214 24 0 0
2012 413 244 221 23 0 0
2013 416 258 223 34 1 0
2014 355 208 185 21 1 1⁵
2015 402 264 244 20 0 0
2016 396 277 248 29 0 0
2017 375 266 247 19 0 0
2018 308 222 202 17 1 0
2019 218 128 100 9 0 0
TOTAL 70746 4306 3848 420 13 4

1Listed based on the year of death or, if not available, on year of referral; 2Cases with suspected prion disease for which brain tissue was submitted; 3Disease acquired in the United Kingdom; 4Disease acquired in the United Kingdom in one case and in Saudi Arabia in the other; 5Disease possibly acquired in a Middle Eastern or Eastern European country; 6Includes 21 cases in which the diagnosis is pending, and 19 inconclusive cases; 7Includes 21 (19 from 2019) cases with type determination pending in which the diagnosis of vCJD has been excluded. 8The sporadic cases include 3748 cases of sporadic Creutzfeldt-Jakob disease (sCJD), 66 cases of Variably Protease-Sensitive Prionopathy (VPSPr) and 34 cases of sporadic Fatal Insomnia (sFI). 9Total does not include 254 Familial cases diagnosed by blood test only.