Chen Zhao, MD, PhD

Associate Professor
Department of Pathology
School of Medicine
Hematopoietic and Immune Cancer Biology Program
Case Comprehensive Cancer Center

Research Information

Research Interests

Our lab is focusing on seeking in-depth understanding of the mechanisms of hematopoietic stem/progenitor cell (HSPC)self-renewal, the interactions of HSPCs and bone marrow microenvironment, and how these become dysregulated to cause leukemia/lymphoma. Specifically, we are focusing on the roles of non-canonical NF-kB signaling and the heat shock factor 1 in the self-renewal of normal hematopoietic stem/progenitor cells and the acute myeloid leukemia stem cells.