Neil S. Greenspan, MD, PhD

Professor
Department of Pathology
School of Medicine

Dr. Neil Greenspan received his A.B., magna cum laude, in Biochemical Sciences from Harvard College in 1975. He then earned M.D. and Ph.D. (Immunology) degrees at the University of Pennsylvania. From 1981 until 1986, Dr. Greenspan was a Resident in Laboratory Medicine (Clinical Pathology) at Barnes Hospital, and from 1982-1985 he was a Postdoctoral Fellow in Molecular Immunology at Washington University, both in St. Louis. In 1986, Dr. Greenspan became a faculty member at the CWRU School of Medicine. He is currently Professor of Pathology at CWRU and the Director of the Histocompatibility and Immunogenetics Laboratory at University Hospitals Cleveland Medical Center. 

Dr. Greenspan is also a senior editor with Pathogens and Immunity, a research journal founded at Case in 2015. Pathogens and Immunity began publishing in 2016.

Research Information

Research Interests

Immune recognition and specificity, immunity to pathogens, transplantation immunology and immunogenetics, evolutionary medicine, human genetics.
I am no longer accepting trainees for experimental research.
 

Awards and Honors

Magna Cum Laude
1975
Harvard College
Detur Prize
1975
Harvard University
Morton McCutcheon Memorial Prize for Laboratory Research in Experimental Pathology
1981
University of Pennsylvania
Elected Fellow
2021
American Association for the Advancement of Science

External Appointments

Title
Director, Histocompatibility and Immunogenetics Laboratory
Organization/Publication
University Hospitals Cleveland Medical Center

Publications

View All Publications

New, J.S., Dizon, BLP, King, R.G., Greenspan, N.S., and Kearney, J.F. B-1 B cell-derived natural antibodies to N-acetyl-D-glucosamine suppress autoimmune diabetes pathogenesis, J. Immunol. doi: 10.4049/jimmunol.2300264. Epub 2023, September 25. (listed as “Top Read” by Journal of Immunology, 11/01/2023; https://journals.aai.org/jimmunol/article/211/9/1253/265966/Top-Reads)

Greenspan, N.S. Epitopes, Paratopes, and Other Topes 30 Years On: Understanding What We are Talking About? Human Immunology 84(9): 429-438. https://doi.org/10.1016/j.humimm.2023.06.006. Epub 2023, July 6. PMID: 37407356 (listed as one of the “Top Articles of 2023” for Human Immunology) 

Greenspan, N.S., and Pereda G.A. Pandemics and the English language: concepts critical for conversing about COVID-19. Pathogens and Immunity, 2022;7(2):78–92. PMID: 36407560



 


 

Education

Doctor of Medicine
University of Pennsylvania
1981
Doctor of Philosophy
University of Pennsylvania
Immunology
1981
Bachelor of Arts
Harvard College
Biochemical Sciences
1975

Residencies, Internships and Fellowships

Postdoctoral Fellowship in Molecular Immunology
Washington University
1985
Residency in Clinical Pathology (Laboratory Medicine)
Barnes Hospital