Mendel E. Singer, PhD, MPH

Associate Professor
Department of Population & Quantitative Health Sciences
School of Medicine
Vice Chair for Education

Dr. Mendel E. Singer plays a significant role in the department leading the development and promotion of graduate programs, which have grown considerably under his direction. In addition to his oversight and teaching responsibilities, his own methods research focuses on innovative use of electronic health records for evidence based medicine and public health and cost-effectiveness analysis in developing nations. His research has focused on the medical areas of opioid overdose, infectious disease and sexual assault.

Teaching Information

Courses Taught

Statistical Methods in Public Health
Comparative and Cost Effectiveness Research
Biostatistics Module, Physician’s Assistant Program

Research Information

Research Interests

Content Areas

  • Public and population health
  • Opioid overdose
  • Health outcomes research
  • Evidence-based public health and medicine


  • Using electronic health records for health outcomes research
  • Using electronic health records for prevention
  • Using electronic health records for comparative and cost-effectiveness research
  • Cost-effectiveness analysis for public health issues

Professional Memberships

American Public Health Association
American Medical Informatics Association


1. Singer ME, Kaelber DC, Antonelli MJ. Hydroxychloroquine
ineffective for COVID-19 prophylaxis in lupus and rheumatoid
Annals of the rheumatic diseases. August 2020.

2. *Deo VS, Gilson TP, Kaspar C, Singer ME. The fentanyl phase of
the opioid epidemic in Cuyahoga County, Ohio, United
Journal of forensic sciences. 2021;66(3):926-933.

3. Lovell RE, Singer M, Flannery DJ, McGuire MJ. The case for
“investigate all”: Assessing the cost-effectiveness of investigating
no CODIS hit cases in a sexual assault kit initiative
Journal of forensic
. 2021;66(4):1316-1328. doi:10.1111/1556-4029.14686

4. Singer ME, Smith MS. Wide Area Transepithelial Sampling with
Computer-Assisted Analysis (WATS 3D ) Is Cost-Effective in
Barrett’s Esophagus Screening
Digestive diseases and sciences.
2021;66(5):1572-1579. doi:10.1007/s10620-020-06412-1

5. Sheikh SR, Kattan MW, Steinmetz M, Singer ME, Udeh BL, Jehi L.
Cost-effectiveness of surgery for drug-resistant temporal lobe
epilepsy in the US
Neurology. 2020;95(10):e1404-e1416.

6. Shah C, Ward MC, Tendulkar RD, Cherian S, Vicini F, Singer ME.
Cost and Cost-Effectiveness of Image Guided Partial Breast
Irradiation in Comparison to Hypofractionated Whole Breast
International journal of radiation oncology, biology,
. 2019;103(2):397-402. doi:10.1016/j.ijrobp.2018.09.021

7. Ward, MC, Shah, C, Adelstein, DJ, Geiger, JL, Miller, JA, Koyfman,
SA, Singer, MECost-effectiveness of nivolumab for recurrent or
metastatic head and neck cancer
☆. Oral Oncol. 2017; 74 : 49-55.
PubMed PMID:29103751.

8. Rose, J, Homa, L, Meropol, SB, Debanne, SM, Bielefeld, R, Hoyen,
C, Singer, MEHealth impact and cost-effectiveness of a
domestically-produced rotavirus vaccine in India: A model
based analysis
PLoS ONE 2017; 12 (11): e0187446.
PubMed PMID:29099848 PubMed Central PMC5669435.

9. Slaughter, ME, Farris, C, Singer, MI, Smyth, KA, Singer, MEUsing
Claims Data to Examine Hospital Readmission Risk in Patients
With Schizophrenia and Comorbid Marijuana Use Disorders
Stud Alcohol Drugs
 2017; 78 (2): 278-286.
PubMed PMID:28317509 .

10. *O’Rourke-Suchoff DK, Arora KS, Hildebrand VM, Singer
Exploring Maternal Attitudes Towards Adolescent
Contraception:Implications for Use of LARC
International Journal
of Adolescent Medicine and Health
. Date of Electronic
Publication: 2017 Jun 09.

11. Schiltz, NK, Kaiboriboon, K, Koroukian, SM, Singer, ME, Love,
TE. Long-term reduction of health care costs and utilization after
epilepsy surgery
Epilepsia 2016; 57 (2): 316-24.
PubMed PMID:26693701 PubMed Central PMC4744096.

12. Callier SL, Abudu R, Mehlman MJ, Singer ME, Neuhauser D,
Caga-Anan C, Wiesner GL. Ethical, legal, and social implications of
personalized genomic medicine research: current literature and
suggestions for the future
Bioethics.  2016 Nov;30(9):698-705.
doi: 10.1111/bioe.12285.

13. Zein, JG, Menegay, MC, Singer, ME, Erzurum, SC, Gildea, TR,
Cicenia, JC, Khatri, S, Castro, M, Udeh, BL. Cost effectiveness of
bronchial thermoplasty in patients with severe uncontrolled
J Asthma 2016; 53 (2): 194-200. PubMed PMID:26377375 .

14. Younossi ZM, Singer ME, Mir HM, Henry L, Hunt S. Impact of
Interferon Free Regimens on Clinical and Cost Outcomes for
Chronic Hepatitis C Genotype 1 Patients
Journal of Hepatology.
2014 Mar; Vol. 60 (3), pp. 530-7. PMID: 24269472

15. *Kagaayi  J; Gray RH; Whalen C; Fu P; Neuhauser D; McGrath
JW; Sewankambo NK; Serwadda D; Kigozi G; Nalugoda F; Reynolds
SJ; Wawer MJ; Singer MEIndices to measure risk of HIV
acquisition in Rakai, Uganda
. PLoS One. 2014 Apr 04; Vol. 9 (4),
pp. e92015. Date of Electronic Publication: 20140404 (Print
Publication: 2014). PMCID: PMC3976261

16. *Musuuzu JS; Singer ME; MandalakasA; Katamba A. Key
actors’ perspectives on cost-effectiveness analysis in Uganda: a
cross-sectional survey
BMC Health Services Research [BMC
Health Serv Res], ISSN: 1472-6963, 2014 Nov 4; Vol. 14 (1), pp.
539. PMID: 25363234

17. Moore-Schiltz L, Albert JM, Singer ME, Swain J, Nock
NL. Dietary intake of calcium and magnesium and the metabolic
syndrome in the National Health and Nutrition Examination
(NHANES) 2001-2010 data
British Journal of Nutrition.  2015 Aug
11, pp. 1-12.


Operations Research
Case Western Reserve University
Case Western Reserve University
Operations Research
Case Western Reserve University
Rutgers University

Additional Information


Student and mentee totals, over Case Western Reserve University career/full academic career:

  • Master’s: Over 500 taught, 54 mentored (11 MS Thesis, 43 MPH Capstone) 
  • PhD: 8 mentored              
  • A sampling of CWRU PhD graduates’ current careers:  
    • University of Washington 
    • World Health Organization
    • Rand Corporation
    • Makerere University School of Public Health
    • Cleveland Clinic
    • University Hospitals of Cleveland
    • Exact Sciences