Clinical Research Curriculum

The Clinical Research Scholar’s Program (CRSP) offers two pathways to obtain a Master’s degree. Each pathway is designed to best meet the needs of each student and to help reach their educational goals.  

Thesis Pathway

30 Credits (15 Credits of Required Coursework; 6 Credits of Elective Coursework; 9 Credits of Thesis Research)

Our educational goal in the thesis pathway is to provide a high quality, rigorous, didactic instruction, and a mentored thesis research project. This pathway is designed for clinicians with an advanced degree who are interested in developing a career in clinical investigation and who are willing to strive for leadership roles in academia, government, and private industry. 

Capstone Pathway 

30 Credit (12 Credits of Required Coursework; 15 Credits of Elective Coursework; 3 Credits of Capstone/Internship Project)

The Capstone pathway is created for individuals with a Bachelor’s degree who are interested in receiving training in clinical research methodologies, serving roles such as study coordinators, research assistants or data managers.

Core Courses

This course is designed to familiarize one with the language and concepts of clinical investigation and statistical computing, as well as provide opportunities for problem-solving, and practical application of the information derived from the lectures. The material is organized along the internal logic of the research process, beginning with mechanisms of choosing a research question and moving into the information needed to design the protocol, implement it, analyze the findings, and draw and disseminate the conclusion(s). Prereq: M.D., R.N., Ph.D., D.D.S., health professionals.

Written communication is a critical skill in clinical science. We disseminate our work to others through publications, and we obtain the resources to conduct research through grant proposals. This course has been developed for Kl2 and CRSP scholars. The course focuses on writing grant proposals and, in particular, specific sections of an NIH-style grant. However, the principles discussed in the course apply to any type of proposal. Prereq: CRSP 401 or equivalent.

To move their work forward, investigators must be able to present their research effectively to both scientific and lay audiences. Although "the written word" is probably the first medium that comes to mind when we think of communication in scientific circles, other modes of communication are also vital. The main objective of this course is to help scholars improve their oral and poster presentation skills, as well as interaction with the mass media. This objective will be achieved through a combination of didactic sessions, readings, and presentations by the students. Prereq: CRSP 401 or equivalent.

Application of statistical techniques with particular emphasis on problems in the biomedical sciences. Basic probability theory, random variables, and distribution functions. Point and interval estimation, regression, and correlation. Problems whose solution involves using packaged statistical programs. First part of year-long sequence. Offered as ANAT 431, BIOL 431, CRSP 431, PQHS 431 and MPHP 431.

Methods of analysis of variance, regression and analysis of quantitative data. Emphasis on computer solution of problems drawn from the biomedical sciences. Design of experiments, power of tests, and adequacy of models. Offered as BIOL 432, PQHS 432, CRSP 432 and MPHP 432. Prereq: PQHS/EPBI 431 or equivalent.

This course is designed to introduce students to the ethical, policy, and legal issues raised by research involving human subjects. It is intended for law students, post-doctoral trainees in health-related disciplines and other students in relevant fields. Topics include (among others): regulation and monitoring of research; research in third-world nations; research with special populations; stem cell and genetic research; research to combat bioterrorism; scientific misconduct; conflicts of interest; commercialization and intellectual property; and the use of deception and placebos. Course will meet once per week for 2 hours throughout the semester. Grades will be given based on class participation and a series of group projects and individual short writing assignments. Offered as BETH 503, CRSP 603 and LAWS 5225.

The Capstone will provide hands-on experience in conducting clinical research. To complete the Capstone project the student will register for 3 credit hours and dedicate at least 160 hours over the course of a semester, typically 20 hours per week for 8 weeks. Under the guidance of a Capstone Advisor the student will develop a Capstone project or internship/practicum, which may take diverse forms: A study project; Internship/Practicum: A combination of tasks necessary for the successful implementation of a study, such as attending team meetings, developing an IRB protocol, designing study forms, assisting with recruitment, study procedures, data management/cleaning, descriptive analysis, secondary analysis; Another format, with approval of CRSP director and Capstone Advisor.

This course provides an introduction to the principles of epidemiology covering the basic methods necessary for population and clinic-based research. Students will be introduced to epidemiologic study designs, measures of disease occurrence, measures of risk estimation, and casual inference (bias, confounding, and interaction) with application of these principles to specific fields of epidemiology. Classes will be a combination of lectures, discussion, and in-class exercises. It is intended for students who have a basic understanding of the principals of human disease and statistics. Offered as PQHS 490 and MPHP 490. Prereq or Coreq: PQHS/EPBI 431 or Requisites Not Met permission.

* Required for Thesis Pathway 

** Required for Capstone Pathway

Capstone Sample Schedule

 
Semester Course Credits
July CRSP 401 Introduction to Clinical Research Summer Series 1-3
CRSP 406 Introduction to R Programming 3
Fall CRSP 431 Statistical Methods I 3
PQHS 490 Epidemiology: Introduction to Theory and Methods  3
CRSP 603 Research Ethics and Regulation 1-2
CRSP 413 Communication in Clinical Research 1
Spring CRSP 432 Statistical Methods II 3
CRSP 504 Managing Research Records 2-3
IBMS 500 On Being a Professional Scientist 1
PQHS 450 Clinical Trials and Intervention Studies 3
Summer CRSP 650 Capstone Experience 3
PQHS 467 Comparative and Cost Effectiveness Analysis in Health Care 3

Electives

Each student is encouraged to develop his/her own program of study based on personal interests and needs. Students are encouraged to consult with CRSP faculty and their Advisor on which electives will best suit their needs.