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Tsan Sam Xiao, PhD
Professor, Department of Pathology, School of MedicineMember, Developmental Therapeutics Program, Case Comprehensive Cancer CenterMember, Center for AIDS Research, School of MedicineMember, Cleveland Center for Membrane and Structural BiologyEmail: tsan.xiao@case.edu
Phone: 216.368.3330
My research focuses on structural and function of gasdermin family members in pyroptosis and inflammatory cytokine secretion, Molecular mechanisms of inflammasome activation during viral infection such as SARS-CoV-2, and Activation and substrate recognition by inflammatory caspases in health and disease.
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Liangqi Xie, PhD
Assistant Staff, Cancer Biology, Lerner Research Institute, Cleveland ClinicMember, Cancer Imaging Program, Case Comprehensive Cancer CenterEmail: xiel2@ccf.org
We are interested in using high-resolution microscopy and high-throughput genomics to understand genome regulation in human development and diseases.
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Wen-Cheng Xiong, MD, PhD
Riuko and Archie G. Co Professor, Department of Neurosciences, School of MedicineEmail: Wen-Cheng.Xiong@case.edu
Phone: 216.368.4865
I study molecular mechanisms underlying neural development, neuro-degeneration, and bone homeostasis.
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Rong Xu, PhD
Professor of Biomedical Informatics, Director, Center for AI in Drug Discovery, School of MedicineMember, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center, School of MedicineEmail: rxx@case.edu
Phone: 216.368.0023
We are interested in developing innovative artificial intelligence, natural language processing, data mining, machine learning, pattern recognition, graph theory, systems biology, knowledge representation and engineering, ontology and other computational algorithms to automatically understand genetic causes of diseases, identify candidate drugs/compounds to treat diseases, elucidate how environmental factors contribute to diseases, and conduct health outcomes research.
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Sichun Yang, PhD
Professor, Department of Nutrition, School of MedicineProfessor, Center for Proteomics and Bioinformatics, School of MedicineProfessor, Department of Pharmacology, School of MedicineProfessor, Department of Physiology and Biophysics, School of MedicineMember, Molecular Oncology Program, Case Comprehensive Cancer CenterEmail: sichun.yang@case.edu
Phone: 216.368.5793
My research focuses on mechanistic studies and therapeutic development for ER-positive breast cancer.
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Vivien C. Yee, PhD
Associate Professor, Department of Biochemistry, School of MedicineDirector of Undergraduate Programs and Vice Chair for Education, Department of Biochemistry, School of MedicineAssociate Professor, Department of Pharmacology, School of MedicineMember, Molecular Oncology Program, Case Comprehensive Cancer CenterEmail: vivien.yee@case.edu
Phone: 216.368.1184
I research the determination of protein molecular structure using X-ray diffraction and correlation with function.
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Dhananjay Yellajoshyula, PhD
Assistant Professor, Department of Neurosciences, School of MedicineEmail: Dhananjay.Yellajoshyula@case.edu
Our lab focuses on understanding the cellular and transcriptional mechanisms regulating myelination and the extra cellular matrix during development and their role in disease and injury.
Dhananjay "Dan" Yellajoshyula's Biography -
Jennifer Yu, MD, PhD
Associate Professor, Department of Molecular Medicine, School of MedicineCo-Leader, Developmental Therapeutics Program, Case Comprehensive Cancer CenterEmail: yuj2@ccf.org
Phone: 216.444.0852
I focus primarily on molecular mechanisms driving glioblastoma cancer initiation and progression.
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Jiujiu Yu, PhD
Associate Professor, Department of Nutrition, School of MedicineEmail: jxy1189@case.edu
Phone: 216.368.3956
Our long-term research goals are to 1) investigate the molecular mechanisms of chronic inflammation in obesity-related metabolic diseases and 2) identify new dietary interventions or molecular therapeutics to suppress such chronic inflammation. We are particularly interested in the contribution of the NLRP3 inflammasome and extracellular vesicles to chronic inflammation. We also actively work on dietary vesicle-like nanoparticles and their anti-inflammatory functions in the context of obesity-related diseases.
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Congrong "Ron" Yu, PhD
Chair, Department of Neurosciences, School of MedicineTilles-Weidenthal Professorship in Parkinson’s Disease and Movement Disorders Research, Department of Neurosciences, School of MedicineEmail: Ron.Yu@case.edu
Phone: 216.368.5159